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Key=created_at, value=2022-06-22 07:53:15
Key=updated_at, value=2024-10-04 05:04:02
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Key=name, value=Anti-Claudin 3/CLDN3 Antibody Picoband® (monoclonal, 4C7D2)
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Key=host, value=Mouse
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Key=price, value=370.0000
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Key=meta_title, value=Anti-Claudin 3/CLDN3 Antibody Picoband® (monoclonal, 4C7D2)
Key=meta_description, value=Boster Bio Anti-Claudin 3/CLDN3 Antibody Picoband® (monoclonal, 4C7D2) catalog # M04393-2. Tested in IF, IHC, WB applications. This antibody reacts with Human.
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Key=url_key, value=anti-claudin-3-cldn3-picoband-trade-antibody-m04393-2-boster
Key=url_path, value=anti-hsp105-hsph1-picoband-trade-antibody-monoclonal-m04168-1-boster
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Key=image_label, value=Figure 1. Western blot analysis of Claudin 3/CLDN3 using anti-Claudin 3/CLDN3 antibody (M04393-2).
Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was load
Key=small_image_label, value=Figure 1. Western blot analysis of Claudin 3/CLDN3 using anti-Claudin 3/CLDN3 antibody (M04393-2).
Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was load
Key=thumbnail_label, value=Figure 1. Western blot analysis of Claudin 3/CLDN3 using anti-Claudin 3/CLDN3 antibody (M04393-2).
Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was load
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Key=size, value=100 μg/vial
Key=gene_full_name, value=heat shock 105kDa/110kDa protein 1
Key=uniprot_id, value=O15551
Key=reconstitution, value=Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Key=sensitivity
Key=applications, value=IF, IHC, WB
Key=reactivity, value=Human
Key=form, value=Lyophilized
Key=concentration, value=Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Key=cross_reactivity, value=No cross-reactivity with other proteins.
Key=recommended_detection_systems, value=Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P).
Key=clone_number, value=4C7D2
Key=source_company, value=Boster M04393-2
Key=isotype, value=Mouse IgG2b
Key=product_category, value=Primary Antibodies
Key=research_category, value=Cell Adhesion Proteins, Epigenetics and Nuclear Signaling, Integrins, Mediator Complex, Neuroscience, Receptors, Transcription
Key=clonality, value=Monoclonal
Key=swatch_image, value=/m/0/m04393-2-cldn3-primary-antibodies-wb-testing-1.jpg
Key=rating_value, value=98.3
Key=review_count, value=6
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Key=cj_related_products, value=Contact Inhibition:A02303-3|A00481-1^Malignant Neoplasm Of Tongue:A01333-1^Prion Diseases:EK2002|EK2003^Swine Diseases:A06655-1
Key=description, value=Boster Bio Anti-Claudin 3/CLDN3 Antibody Picoband® (monoclonal, 4C7D2) catalog # M04393-2. Tested in IF, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=short_description, value=Boster Bio Anti-Claudin 3/CLDN3 Antibody Picoband® (monoclonal, 4C7D2) catalog # M04393-2. Tested in IF, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=meta_keyword, value=Anti-Claudin 3/CLDN3 Antibody Picoband® (monoclonal, 4C7D2)
Key=contents, value=Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
Key=background, value=Claudin 3, also known as CLDN3, is a protein which in humans is encoded by the CLDN3 gene. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.
Key=gene_name, value=CLDN3
Key=synonyms, value=Heat shock protein 105 kDa; Antigen NY-CO-25; Heat shock 110 kDa protein; HSPH1; HSP105; HSP110; KIAA0201
Key=application_details, value=Western blot, 0.25-0.5 μg/ml, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human
Immunofluorescence, 5 μg/ml, Human

Key=subcellular_localization, value=Cytoplasm.
Key=tissue_specificity, value=Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.
Key=protein_function, value=Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering client/substrate protein release. Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities.
Key=application_notes, value=Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Key=immunogen, value=E.coli-derived human Claudin 3/CLDN3 recombinant protein (Position: A101-V220).
Key=purification, value=Immunogen affinity purified.
Key=storage, value=At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
Key=custom_attribute_1, value=20 kDa
Key=custom_attribute_2, value=WB: human MCF-7 whole cell, human CACO-2 whole cell
IHC: human colorectal adenocarcinoma tissue, human colorectal adenocarcinoma tissue, human lung adenocarcinoma tissue
IF: human lung adenocarcinoma tissue
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