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Key=created_at, value=2020-07-06 01:48:05
Key=updated_at, value=2024-09-26 01:15:51
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Key=name, value=Anti-Claudin 3/CLDN3 Antibody Picoband®
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Key=meta_title, value=Claudin 3/CLDN3 Antibody A04393-4
Key=meta_description, value=Boster Bio Anti-Claudin 3/CLDN3 Antibody Picoband® catalog # A04393-4. Tested in IF, ICC, WB applications. This antibody reacts with Mouse, Rat. Supplied as 100μg/vial in Lyophilized form antibody.
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Key=image_label, value=Figure 1. IF analysis of Claudin 3/CLDN3 using anti-Claudin 3/CLDN3 antibody (A04393-4).
Claudin 3/CLDN3 was detected in immunocytochemical section of NIH/3T3 cells. Enzyme antigen retrieval was performed using IHC enzyme antigen retrieval reagent (
Key=small_image_label, value=Figure 1. IF analysis of Claudin 3/CLDN3 using anti-Claudin 3/CLDN3 antibody (A04393-4).
Claudin 3/CLDN3 was detected in immunocytochemical section of NIH/3T3 cells. Enzyme antigen retrieval was performed using IHC enzyme antigen retrieval reagent (
Key=thumbnail_label, value=Figure 1. IF analysis of Claudin 3/CLDN3 using anti-Claudin 3/CLDN3 antibody (A04393-4).
Claudin 3/CLDN3 was detected in immunocytochemical section of NIH/3T3 cells. Enzyme antigen retrieval was performed using IHC enzyme antigen retrieval reagent (
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Key=size, value=100 μg/vial
Key=gene_full_name, value=acyl-CoA synthetase long chain family member 4
Key=uniprot_id, value=Q9Z0G9
Key=reconstitution, value=Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Key=sensitivity
Key=applications, value=IF, ICC, WB
Key=reactivity, value=Mouse, Rat
Key=form, value=Lyophilized
Key=concentration, value=Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Key=cross_reactivity, value=No cross-reactivity with other proteins.
Key=recommended_detection_systems, value=Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for ICC.
Key=source_company, value=Boster A04393-4
Key=isotype, value=Rabbit IgG
Key=sample_size_available, value=30ug for $99, contact us for details
Key=related_product_skus, value=B0001-5,AR1156,AR0146
Key=product_category, value=Primary Antibodies
Key=research_category, value=Adaptive Immunity, B Cells, Hematopoietic Progenitors, Immunoglobulins, Immunology, Lymphoid, Receptors, Stem Cells
Key=clonality, value=Polyclonal
Key=swatch_image, value=/a/0/a04393-4-cldn3-primary-antibodies-if-testing-1.jpg
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Key=cj_related_products, value=Cystadenocarcinoma, Serous:A04393-3^Germ Cell Migration:A00643-2|A06975-1|EKC2608|A04393-3
Key=out_of_stock_until_date, value=Nov 16, 2019
Key=description, value=Boster Bio Anti-Claudin 3/CLDN3 Antibody Picoband® catalog # A04393-4. Tested in IF, ICC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=short_description, value=Boster Bio Anti-Claudin 3/CLDN3 Antibody Picoband® catalog # A04393-4. Tested in IF, ICC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=meta_keyword, value=Anti-Claudin 3/CLDN3 Antibody Picoband®
Key=contents, value=Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.
Key=background, value=Claudin 3, also known as CLDN3, is a protein which in humans is encoded by the CLDN3 gene. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a low-affinity receptor for clostridium perfringens enterotoxin (CPE) produced by the bacterium Clostridium perfringens, and the interaction with CPE results in increased membrane permeability by forming small pores in plasma membrane. This protein is highly overexpressed in uterine carcinosarcoma. This protein is also predominantly present in brain endothelial cells, where it plays a specific role in the establishment and maintenance of blood brain barrier tight junction morphology.
Key=gene_name, value=Cldn3
Key=synonyms, value="Long-chain-fatty-acid--CoA ligase 4; Long-chain acyl-CoA synthetase 4; LACS 4; ACSL4; ACS4, FACL4, LACS4 "
Key=application_details, value=Western blot, 0.25-0.5μg/ml, Rat
Immunocytochemistry/Immunofluorescence, 5μg/ml, Mouse

Key=subcellular_localization, value= Secreted.
Key=tissue_specificity, value= Expressed in the prostate gland and prostate cancers.
Key=protein_function, value=Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:24269233, PubMed:22633490, PubMed:21242590). Preferentially activates arachidonate and eicosapentaenoate as substrates (PubMed:21242590). Preferentially activates 8,9-EET > 14,15-EET > 5,6-EET > 11,12-EET. Modulates glucose-stimulated insulin secretion by regulating the levels of unesterified EETs (By similarity). Modulates prostaglandin E2 secretion (PubMed:21242590).
Key=application_notes, value=Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Key=immunogen, value=A synthetic peptide corresponding to a sequence at the C-terminus of mouse Claudin 3/CLDN3, which shares 73.3% and 94.1% amino acid (aa) sequence identity with human and rat Claudin 3/CLDN3, respectively.
Key=purification, value=Immunogen affinity purified.
Key=storage, value=Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Key=custom_attribute_1, value=23 kDa
Key=custom_attribute_2, value=WB: rat PC-12 whole cell
ICC/IF: NIH/3T3 cell
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