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Product Info Summary
| SKU: | R00804 |
|---|---|
| Size: | 100μg/vial |
| Origin Species: | Human |
| Source: | E. coli A26-R221 |
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Product info
Product Name
Recombinant Human OSM Protein
View all Oncostatin M/OSM recombinant proteins
SKU/Catalog Number
R00804
Size
100μg/vial
Description
Oncostatin-M (OSM) is amember of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophagecolony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Storage & Handling
Lyophilized recombinant human Oncostatin-M remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, OSM remains stable up to 2 weeks at 4°C or up to 3 months at -20°C.
Cite This Product
Recombinant Human OSM Protein (Boster Biological Technology, Pleasanton CA, USA, Catalog # R00804)
Form
Lyophilized
Formulation
Reconstitute in ddH2O at 100 μg/mL.
Purity
>95%, by SDS-PAGE quantitative densitometry by Coomassie® Blue Staining.
Predicted MW
22KD
Endotoxin
Less than 1 EU/μg of OSM as determined by LAL method.
Amino Acid Sequence
AAIGS CSKEY RVLLG QLQKQ TDLMQ DTSRL LDPYI RIQGL DVPKL REHCR ERPGA FPSEE TLRGL GRRGF LQTLN ATLGC VLHRL ADLEQ RLPKA QDLER SGLNI EDLEK LQMAR PNILG LRNNI YCMAQ LLDNS DTAEP TKAGR GASQP PTPTP ASDAF QRKLE GCRFL HGYHR FMHSV GRVFS KWGES PNRSR
Assay dilution & Images
Validation Images & Assay Conditions
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Boster Kit Box
Protein Target Info & Infographic
Gene/Protein Information For OSM (Source: Uniprot.org, NCBI)
Gene Name
OSM
Full Name
Oncostatin-M
Weight
22KD
Superfamily
LIF/OSM family
Alternative Names
MGC20461; oncostatin M; oncostatin-M; OSM OSM oncostatin M oncostatin-M
*If product is indicated to react with multiple species, protein information is based on the gene entry specified above in "Species".For more info on OSM, check out the OSM Infographic
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In this infographic, you will see the following information for OSM: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us at [email protected].
Specific Publications For Recombinant Human OSM Protein (R00804)
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