Recombinant Human FGF2 Protein

Product Name

Recombinant Human FGF2 Protein

View all FGF basic/FGF2/bFGF recombinant proteins

SKU/Catalog Number

R00121

Size

100μg/vial

Description

Fibroblast Growth Factor basic (FGF-basic/FGF-2) is a single-chain polypeptide growth factor that plays a significant role in the process of wound healing and is a potent inducer of angiogenesis. Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 gene. It has a 55 percent amino acid residue identity to FGF-1 and has potent heparin-binding activity. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor. Other homologous FGF belonging to the same family are int-2 (FGF-3), FGF-5, FGF-6, K-FGF and KGF ( keratinocyte growth factor = FGF-7). All factors are products of different genes, some of which are Oncogene products ( FGF-3, FGF-4, FGF-5 ).

Storage & Handling

Lyophilized recombinant mouse Fibroblast Growth Factor basic (FGF-basic/FGF-2) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhFGF2 remains stable up to 2 weeks at 4°C or up to 3 months at -20°C.

Cite This Product

Recombinant Human FGF2 Protein (Boster Biological Technology, Pleasanton CA, USA, Catalog # R00121)

Form

Lyophilized

Formulation

Lyophilized after extensive dialysis against PBS.

Purity

>95%, by SDS-PAGE quantitative densitometry by Coomassie® Blue Staining.

Predicted MW

16.5KD

Endotoxin

Less than 1 EU/μg of rHubFGF as determined by LAL method.

Validation Images & Assay Conditions

Gene/Protein Information For FGF2 (Source: Uniprot.org, NCBI)

Alternative Names

basic fibroblast growth factor bFGF; Basic fibroblast growth factor; bFGF; FGF basic; FGF2; FGF-2; FGFBprostatropin; fibroblast growth factor 2 (basic); HBGF-2; heparin-binding growth factor 2; Prostatropin FGF2 BFGF, FGF-2, FGFB, HBGF-2 fibroblast growth factor 2 fibroblast growth factor 2|basic fibroblast growth factor bFGF|fibroblast growth factor 2 (basic)|heparin-binding growth factor 2|prostatropin

*If product is indicated to react with multiple species, protein information is based on the gene entry specified above in "Species".

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