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FGF2 Antibodies
AND FGF2 ELISA kits, FGF2 Proteins
Many biological assays use antibodies to detect FGF2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FGF2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FGF2 antibodies...
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FGF2 Infographic by Boster Bio
All FGF2 Products
Product
Figures
Specificity
Applications
Price
Anti-Fibroblast growth factor 2 FGF2 Antibody Picoband®
7 Citations 16 Q&As
Human
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # RP1006
100 μg/vial
Cat # RP1006
100 μg/vial
Anti-FGF2/Fgf Basic Rabbit Monoclonal Antibody
3 Citations 16 Q&As
Human
Flow Cytometry, IP, WB
$370
Cat # M00121
100 μl
Cat # M00121
100 μl
Rat
$250
Cat # PROTP13109
10ug, 50ug, 1mg
Cat # PROTP13109
10ug, 50ug, 1mg
Mouse
$250
Cat # PROTP15655
10ug, 50ug, 1mg
Cat # PROTP15655
10ug, 50ug, 1mg
Anti-FGF2 Antibody Picoband®
6 Citations 15 Q&As
Human
ELISA, IF, IHC, ICC, WB
$370
Cat # A00121-1
100 μg/vial
Cat # A00121-1
100 μg/vial
Human
ELISA
$500
Cat # EZ0342
For 5 plates, 96 wells each
Cat # EZ0342
For 5 plates, 96 wells each
Human FGF2 ELISA Kit PicoKine®
7 Citations 12 Q&As
Human
ELISA
$499
Cat # EK0342
96 wells/kit, with removable strips.
Cat # EK0342
96 wells/kit, with removable strips.
Human, Mouse, Rat
IF, IHC, WB
$523
Cat # M00121-2
100 µl
Cat # M00121-2
100 µl
Human, Mouse, Rat
Flow Cytometry, WB
$523
Cat # M00121-3
100 µl
Cat # M00121-3
100 µl
Anti-FGF2 Antibody Picoband®
6 Citations
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # A00121-3
100 μg/vial
Cat # A00121-3
100 μg/vial
Mouse
Cell Culture
$77
Cat # PROTP15655-2
20ug,100ug,500ug
Cat # PROTP15655-2
20ug,100ug,500ug
Swine
Cell Culture
$154
Cat # PROTA0A287BGK8
5ug,20ug
Cat # PROTA0A287BGK8
5ug,20ug
Human
Cell Culture
$77
Cat # PROTP09038-10
20ug,100ug,500ug
Cat # PROTP09038-10
20ug,100ug,500ug
Cynomolgus monkey, Human
ELISA, Flow Cytometry, FTA
$349
Cat # M00121-4
100 &mug
Cat # M00121-4
100 &mug
FGF2 Overview
Facts about Fibroblast growth factor 2.
Fibroblast growth factor 2 (FGF2)
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 (PubMed:8663044).
Also acts as an integrin ligand that's required for FGF2 signaling (PubMed:28302677).Binds to integrin ITGAV:ITGB3 (PubMed:28302677). Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration (PubMed:8663044, PubMed:28302677).
Gene Information
| Human | |
|---|---|
| Gene Name: | FGF2 |
| Uniprot: | P09038 |
| Entrez: | 2247 |
Family
| Belongs to: |
|---|
| heparin-binding growth factors family |
Alternative Names
basic fibroblast growth factor bFGF; Basic fibroblast growth factor; bFGF; FGF basic; FGF2; FGF-2; FGFBprostatropin; fibroblast growth factor 2 (basic); HBGF-2; heparin-binding growth factor 2; Prostatropin
Molecular Weight
Mass (kDA):
30.77 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q28.1 |
| Sequence: | 4; NC_000004.12 (122826708..122898236) |
Tissue Specificity
Expressed in granulosa and cumulus cells. Expressed in hepatocellular carcinoma cells, but not in non- cancerous liver tissue.
Subcellular Localizations
Secreted. Nucleus. Exported from cells by an endoplasmic reticulum (ER)/Golgi-independent mechanism. Unconventional secretion of FGF2 occurs by direct translocation across the plasma membrane. Binding of exogenous FGF2 to FGFR facilitates endocytosis followed by translocation of FGF2 across endosomal membrane into the cytosol. Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as CEP57.
Diseases
- Tumor Angiogenesis
- Neoplasms
- Malignant Neoplasms
- Pathologic Neovascularization
- Tissue Adhesions
- Carcinoma
- Nervousness
- Malignant Paraganglionic Neoplasm
- Hyperplasia
- Mammary Neoplasms
- Craniosynostosis
- Inflammation
Interacting Proteins
- CASP1
- FGFBP1
- FGFR1
- FGFR2
- PTX3
Pathways
- Angiogenesis
- Cell Proliferation
- Regeneration
- Cell Growth
- Secretion
- Cell Cycle
- Neurogenesis
- Cell Death
- Localization
- Cell Differentiation
- Cell Migration
- Wound Healing
- Cell Adhesion
PTMs
- Phosphorylation
- Cleavage
- Glycosylation
- Dephosphorylation
- Methylation
- Acetylation
- Biotinylation
- Reduction
- Oxidation
- Sulphation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FGF2
bosterbio.com/bosterbio-gene-info-cards/FGF2
References
PMID: 3472745 by Abraham J.A., et al. Human basic fibroblast growth factor: nucleotide sequence, genomic organization, and expression in mammalian cells.
PMID: 3780670 by Abraham J.A., et al. Human basic fibroblast growth factor: nucleotide sequence and genomic organization.
24 Publications of Boster FGF2 Antibodies & ELISA Kits
- PubMed ID: PMID:25419401, Effect of angiogenesis inhibitor SU6668 in combination with 5-Fu on liver metast...
- PubMed ID: 10.1111/j.1463-5224.2009.00696.x, Basic fibroblast growth factor stimulates epithelial cell growth and epithelial ...
- PubMed ID: 10.1080/1028602042000325609, Effects of isoliensinine on angiotensin II-induced proliferation of porcine coro...
- PubMed ID: 10.1039/D1TB00515D, Construction of AuHQ nano-sensitizer for enhanced radiotherapy efficacy through ...
- PubMed ID: 10.1039/D1BM00834J, An oxidation responsive nano-radiosensitizer increases radiotherapy efficacy by ...
- PubMed ID: 10.1016/j.pdpdt.2019.05.025, The impact of Aggregatibacter actinomycetemcomitans biofilm-derived effectors fo...
- PubMed ID: 10.1016/j.ejphar.2016.03.021, In vitro and in vivo study of hydralazine, a potential anti-angiogenic agent
- PubMed ID: 10.1016/j.bcp.2019.06.025, FGF-2 signaling activation in the hippocampus contributes to the behavioral and ...
- PubMed ID: 10.1016/j.bbrc.2017.06.041, MiR-129-5p inhibits non-small cell lung cancer cell stemness and chemoresistance...
- PubMed ID: 10.1016/j.actbio.2019.10.011, Biomimetic hydrogel for rapid and scar-free healing of skin wounds inspired by t...
- PubMed ID: 10.1002/jor.22811, Osteogenesis and mineralization in a rabbit mandibular distraction osteogenesis ...
- PubMed ID: , Self‐Adaptive All‐In‐One Delivery Chip for Rapid Skin Nerves Regeneration ...
- PubMed ID: , Overcoming Autocrine FGF Signaling-Induced Heterogeneity in Naive Human ESCs Ena...
- PubMed ID: -, Bing-Jie Hu,Jia-Zhen Zhu,Sequence and time course of depletion of cardiac cellul...
- PubMed ID: 31897132, Chen X,Zhao H,Chen C,Li J,He J,Fu X,Zhao H.The HPA/SDC1 axis promotes invasion a...
- PubMed ID: 30352200, Calcitonin gene-related peptide inhibits the cardiac fibroblasts senescence in c...
- PubMed ID: 26870239, Effect of CPU-XT-008, a combretastatin A-4 analogue, on the proliferation, apopt...
- PubMed ID: 26352430, Astragalosides promote angiogenesis via vascular endothelial growth factor and b...
- PubMed ID: 23129015, Advanced glycation end-products stimulate basic fibroblast growth factor express...
- PubMed ID: 23352645, Zhou B, Ma R, Si W, Li S, Xu Y, Tu X, Wang Q. Cancer Lett. 2013 Jun 10;333(2):15...
- PubMed ID: 25913359, Hu C, Zhang T, Ren B, Deng Z, Cai L, Lei J, Ping A. Med Sci Monit. 2015 Apr 27;2...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page