Disease Info Card

Chromosome Fragility

Information about Chromosome Fragility: characteristics, related genes and pathways, plus antibodies you can use for research. This page is being enriched constantly, if you see some information you would like this page to include please send your suggestions to us.

Overview of Chromosome Fragility

Most recent studies have shown that Chromosome Fragility shares some biological mechanisms with anemia, carcinoma, cell-transformation-neoplastic, chromosomal-translocation, chromosome-breakage, cytogenetic-abnormality, fanconi-anemia, fragile-x-syndrome, fraxa-syndrome, genomic-instability, instabilities-chromosomal, leukemia, leukemia-myelocytic-acute, lymphoma, malignant-neoplasms, malignant-paraganglionic-neoplasm, myeloid-leukemia, neoplasms, sex-chromosome-aberrations.

Among the many pathways, these few ones have gauged particular interests from scientists studying Chromosome Fragility, and have been seen in publications frequently: Aging, Cell Cycle, Cell Division, Cell Growth, Cell Proliferation, Chromosome Breakage, Dna Methylation, Dna Repair, Dna Replication, Hypersensitivity, Interphase, Localization, Metaphase, Methylation, Mismatch Repair, Mitosis, Oncogenesis, Pathogenesis, Reverse Transcription, S Phase

Quite a number of genes have been found to play important roles in Chromosome Fragility, such as ABL1, AFF2, BCR, CDK2AP2, CDKN2A, FHIT, FMR1, FOSL1, FST, GBGT1, NBN, RABEP2, RPP14, S100A9, SUB1, TP53, WWOX. See what Boster has to offer for the research of these genes by clicking the gene name links below and view a more detailed info card/product listing for that gene.

In a later update, we will include information such as current drugs and therapy solutions as well as on-going and past clinical trials for this disease. Plesae stay updated.

Chromosome Fragility Related Genes

click to see detail information for each gene

ABL1 AFF2 BCR
CDK2AP2 CDKN2A FHIT
FMR1 FOSL1 FST
GBGT1 NBN RABEP2
RPP14 S100A9 SUB1
TP53 WWOX