Anti-TORC1 monoclonal CRTC1 Antibody

Product Name

Anti-TORC1 monoclonal CRTC1 Antibody

View all TORC1 Antibodies

SKU/Catalog Number

M01951-1

Size

100ul

Form

Liquid

Description

Boster Bio Anti-TORC1 monoclonal CRTC1 Antibody catalog # M01951-1. Tested in WB applications. This antibody reacts with Human,Mouse,Rat,Monkey.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-TORC1 monoclonal CRTC1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01951-1)

Host

Mouse

Contents

Mouse IgM, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Monoclonal

Clone Number

2D10F4

Isotype

IgG

Immunogen

Synthesized peptide derived from human OCT1 Monoclonal Antibody

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M01951-1 is reactive to CRTC1 in Human, Monkey, Mouse, Rat

Applications

M01951-1 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

67300 MW

Background of TORC1

Indoleamine 2, 3-dioxygenase1 (IDO1) is a 41-42 kD intracellular enzyme that catabolizes tryptophan into kynurenine. IDO1 modulates levels of the amino acid tryptophan, which is vital for cell growth, but is also involved in the suppression of the immune response. IDO1 effects on immune suppression are due to decreased tryptophan availability and the generation of tryptophan metabolites, resulting in negative effects on T lymphocytes, including proliferation, function and survival. IDO1 may be involved in the suppression of the immune response to tumors, and blocking the IDO1 pathway may be a potential target for immuno and cancer therapy. IDO1 is expressed in a wide variety of tissues and can be upregulated by interferon gamma and other inflammatory cytokines.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:1000-2000

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For CRTC1 (Source: Uniprot.org, NCBI)

Alternative Names

CREB regulated transcription coactivator 1; CRTC1; FLJ14027WAMTP1; KIAA0616Transducer of regulated cAMP response element-binding protein 1; MECT1; MECT1CREB-regulated transcription coactivator 1; mucoepidermoid carcinoma translocated 1; Mucoepidermoid carcinoma translocated protein 1; TORC1; TORC1TORC-1; Transducer of CREB protein 1; transducer of regulated cAMP response element-binding protein (CREB) 1; WAMTP1 CRTC1 MAML2, MECT1, Mam-2, TORC-1, TORC1, WAMTP1 CREB regulated transcription coactivator 1 CREB-regulated transcription coactivator 1|Mastermind-like protein 2|mucoepidermoid carcinoma translocated protein 1|transducer of regulated cAMP response element-binding protein (CREB) 1

For more info on CRTC1, check out the CRTC1 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CRTC1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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