Product Info Summary
SKU: | M01951 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Mouse |
Application: | Flow Cytometry, IP, ICC, WB |
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Product info
Product Name
Anti-TORC1 (N-terminus) monoclonal CRTC1 Antibody
SKU/Catalog Number
M01951
Size
100ul
Form
Liquid
Description
Boster Bio Anti-TORC1 (N-terminus) monoclonal CRTC1 Antibody catalog # M01951. Tested in WB,Flow Cytometry,ICC,IP applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-TORC1 (N-terminus) monoclonal CRTC1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01951)
Host
Mouse
Contents
Mouse IgM, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Monoclonal
Clone Number
2D10F4
Isotype
IgG
Immunogen
Synthesized peptide derived from human OCT1 Monoclonal Antibody
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M01951 is reactive to CRTC1 in Human
Applications
M01951 is guaranteed for Flow Cytometry, IP, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
67300 MW
Background of TORC1
Indoleamine 2, 3-dioxygenase1 (IDO1) is a 41-42 kD intracellular enzyme that catabolizes tryptophan into kynurenine. IDO1 modulates levels of the amino acid tryptophan, which is vital for cell growth, but is also involved in the suppression of the immune response. IDO1 effects on immune suppression are due to decreased tryptophan availability and the generation of tryptophan metabolites, resulting in negative effects on T lymphocytes, including proliferation, function and survival. IDO1 may be involved in the suppression of the immune response to tumors, and blocking the IDO1 pathway may be a potential target for immuno and cancer therapy. IDO1 is expressed in a wide variety of tissues and can be upregulated by interferon gamma and other inflammatory cytokines.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1000
ICC: 1:100-300
IP: 1:50-200
FC: 1:50-100
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For CRTC1 (Source: Uniprot.org, NCBI)
Gene Name
CRTC1
Full Name
CREB-regulated transcription coactivator 1
Weight
67300 MW
Superfamily
TORC family
Alternative Names
CREB regulated transcription coactivator 1; CRTC1; FLJ14027WAMTP1; KIAA0616Transducer of regulated cAMP response element-binding protein 1; MECT1; MECT1CREB-regulated transcription coactivator 1; mucoepidermoid carcinoma translocated 1; Mucoepidermoid carcinoma translocated protein 1; TORC1; TORC1TORC-1; Transducer of CREB protein 1; transducer of regulated cAMP response element-binding protein (CREB) 1; WAMTP1 CRTC1 MAML2, MECT1, Mam-2, TORC-1, TORC1, WAMTP1 CREB regulated transcription coactivator 1 CREB-regulated transcription coactivator 1|Mastermind-like protein 2|mucoepidermoid carcinoma translocated protein 1|transducer of regulated cAMP response element-binding protein (CREB) 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CRTC1, check out the CRTC1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CRTC1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TORC1 (N-terminus) monoclonal CRTC1 Antibody (M01951)
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