Anti-TIMP2 (Tissue Inhibitor of Metalloproteinase 2) Monoclonal Antibody

SKU M01037
Size 100ug/vial
Reactivity Bovine, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat, Zebrafish
Clonality Monoclonal
Clone Number SPM356
Host Mouse
Applications IHC

Overview

Product Name Anti-TIMP2 (Tissue Inhibitor of Metalloproteinase 2) Monoclonal Antibody
SKU/Catalog Number M01037
Size 100ug/vial
Description Anti-TIMP2 (Tissue Inhibitor of Metalloproteinase 2) Antibody
Cite This Product Anti-TIMP2 (Tissue Inhibitor of Metalloproteinase 2) Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01037)
Host Mouse
Contents/Buffer Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Form Liquid
Immunogen A synthetic peptide from the N-terminus of human TIMP2 protein (aa56-66) (DSGNDIYGNPI)
Reactivity Bovine, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat, Zebrafish

Assay Details

Assay Dilutions Overview

Concentration: 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Immunohistology (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
Immunofluorescence (0.5-1ug/ml)

Images And Assay Conditions

Formalin-fixed, paraffin-embedded human Placenta stained withTIMP2 Monoclonal Antibody (SPM356).

Target Info

Protein Target Info (Source: Uniprot.org)

Uniprot Id P16035
Gene Name TIMP2
Protein Name Metalloproteinase inhibitor 2
Alternative Names Metalloproteinase inhibitor 2;CSC-21K;Tissue inhibitor of metalloproteinases 2;TIMP-2;TIMP2;
Subcellular Localization Secreted.
Molecular Weight 24399 MW

*if product is indicated to react with multiple species, protein info is based on the human gene.

Ontology

Protein Function Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19. .
Research Areas Bovine, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat, Zebrafish

*You can search these to find other products in these research areas.

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In stock
Order Product
M01037
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$299.00

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Publications

Effect of Novel Gasotransmitter hydrogen sulfide on renal fibrosis and connexins expression in diabetic rats
Effect of norcantharidin on proliferation and invasion of human gallbladder carcinoma GBC-SD cells
The inhibition of calpains ameliorates vascular restenosis through MMP2/TGF-?1 pathway
Inhibition of Zymosan-Induced Inflammatory Factors Expression by ATRA Nanostructured Lipid Carriers
Wu Ty, Zhang Th, Qu Lm, Feng Jp, Tian Ll, Zhang Bh, Li Dd, Sun Yn, Liu M. Int J Clin Exp Pathol. 2013 Dec 15;7(1):56-63. Ecollection 2014. Mir-19A Is Correlated With Prognosis And Apoptosis Of Laryngeal Squamous Cell Carcinoma By Regulating Timp-2...
Shan A, Zhou C, He Y, Feng W, Chen G, Zhong G. Ren Fail. 2013;35(1):37-42. Doi: 10.3109/0886022X.2012.741645. Epub 2012 Nov 14. Expression Of Both Matrix Metalloproteinase-2 And Its Tissue Inhibitor-2 In Tunica Media Of Radial Artery In Uremic Pat...
Zhang Jt, Fan Yz, Chen Cq, Zhao Zm, Sun W. Int J Oncol. 2012 May;40(5):1501-14. Doi: 10.3892/Ijo.2011.1314. Epub 2011 Dec 21. Norcantharidin: A Potential Antiangiogenic Agent For Gallbladder Cancers In Vitro And In Vivo.
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