TIMP2 Antibodies

AND TIMP2 ELISA kits, TIMP2 Proteins

Many biological assays use antibodies to detect TIMP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TIMP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TIMP2 antibodies...

We validate the specificity of these antibodies to TIMP2 by testing them on tissues known to express TIMP2 positively and negatively. Browse below to find the TIMP2 antibody that suites your experiment. We have 11 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: NKX2-1

TIMP2 Infographic by Boster Bio

All TIMP2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-TIMP2 Antibody Picoband®

16 Citations 1 Q&As

Human, Mouse, Rat

$370
Cat # PB9830
100 μg/vial

Human TIMP-2 ELISA Kit PicoKine®

14 Citations 9 Q&As

Human

ELISA

$499
Cat # EK0522
96 wells/kit, with removable strips.

Mouse TIMP-2 ELISA Kit PicoKine®

6 Citations 10 Q&As

Mouse

ELISA

$499
Cat # EK0955
96 wells/kit, with removable strips.

Rat TIMP-2 ELISA Kit PicoKine®

7 Citations 7 Q&As

Rat

ELISA

$499
Cat # EK1302
96 wells/kit, with removable strips.

Anti-Metalloproteinase inhibitor 2 TIMP2 Antibody

16 Citations

Human, Mouse, Rat

ELISA, IHC

$370
Cat # PA1076
100 μg/vial

Anti-TIMP2 (Tissue Inhibitor of Metalloproteinase 2) Monoclonal Antibody

7 Citations 4 Q&As

Cow, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish

Flow Cytometry, IF, IHC, WB

$486
Cat # M01037
100ug/vial

Anti-TIMP2 Rabbit Monoclonal Antibody

4 Citations

Human

Flow Cytometry, WB

$370
Cat # M01037-1
100 μl

Human TIMP-2 PicoKine® Quick ELISA Kit

1 Citations 1 Q&As

Human

ELISA

$499
Cat # FEK0522
96 wells/kit, with removable strips.

Human TIMP-2 Recombinant Protein

SDS-PAGE

$250
Cat # PROTP16035
Starting from 4ug

Anti-TIMP2 Mouse Monoclonal Antibody [Clone ID: OTI1A6]

Dog, Human, Monkey, Mouse, Rat

Flow Cytometry, IHC, WB

$523
Cat # M01037-2
100 µl

TIMP2 (NM_003255) Human Over-expression Lysate

Human

$628
Cat # LS007077
100 µg

TIMP2 Overview

Facts about Metalloproteinase inhibitor 2.

TIMP2 3D structure. Source: alphafold

Metalloproteinase inhibitor 2 (TIMP2)

Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.

Gene Information

Human
Gene Name:	TIMP2
Uniprot:	P16035
Entrez:	7077

Family

Belongs to:

protease inhibitor I35 (TIMP) family

Alternative Names

CSC-21Ktissue inhibitor of metalloproteinase 2; metalloproteinase inhibitor 2; TIMP metallopeptidase inhibitor 2; TIMP2; TIMP-2; Tissue inhibitor of metalloproteinases 2

Molecular Weight

Mass (kDA):
24.399 kDA

Genomic Context


Human

Location:	17q25.3
Sequence:	17; NC_000017.11 (78852977..78925387, complement)

Subcellular Localizations

Secreted.

Diseases

Neoplasms
Malignant Neoplasms
Cell Invasion
Neoplasm Metastasis
Carcinoma
Neoplasm Invasiveness
Fibrosis
Tumor Angiogenesis
Malignant Paraganglionic Neoplasm
Inflammation
Tissue Adhesions
Pathologic Neovascularization

Adenocarcinoma
Cardiovascular Diseases
Endometrial Polyp
Kidney Diseases
Lung Neoplasms
Malignant Neoplasm Of Breast
Liver Neoplasms

Interacting Proteins

MMP14
MMP2

Pathways

Angiogenesis
Pathogenesis
Localization
Cell Migration
Cell Proliferation
Secretion
Tissue Remodeling
Proteolysis
Reverse Transcription
Cell Adhesion
Methylation
Cell Growth
Cell Motility

Dna Methylation
Wound Healing
Regeneration
Cell Cycle
Transport
Invasive Growth
Cell Death

PTMs

Phosphorylation
Cleavage
Methylation
Demethylation

Reduction
Acetylation
Dephosphorylation
Oxidation

Ribosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TIMP2

References

PMID: 2380196 by Stetler-Stevenson W.G., et al. Tissue inhibitor of metalloproteinases-2 (TIMP-2) mRNA expression in tumor cell lines and human tumor tissues.

PMID: 2157214 by Boone T.C., et al. cDNA cloning and expression of a metalloproteinase inhibitor related to tissue inhibitor of metalloproteinases.

33 Publications of Boster TIMP2 Antibodies & ELISA Kits

PubMed ID: 10.3233/CH-151928, Gelatinases and their tissue inhibitors in a group of subjects with obstructive ...
PubMed ID: 10.3233/CH-141863, Behaviour of the plasma concentration of gelatinases and their tissue inhibitors...
PubMed ID: 10.2310/JIM.0b013e318294e9da, Gelatinases and Their Tissue Inhibitors in a Group of Subjects With Metabolic Sy...
PubMed ID: 10.2147/CMAR.S233776, MMP-2, MMP-9, TIMP-1, and TIMP-2 in the Peripheral Blood of Patients with Differ...
PubMed ID: 10.1007/s11255-017-1654-3, High glucose stimulates cell proliferation and Collagen IV production in rat mes...
PubMed ID: 10.1007/s10072-021-05314-y, Expression pattern of matrix metalloproteinases-2 and -9 and their tissue inhibi...
PubMed ID: 10.1007/s00296-011-2095-4, Implication of MMP-9 and urokinase plasminogen activator (uPA) in the activation...
PubMed ID: 33988800, Cosentino G,Di Stefano V,Presti RL,Montana M,Todisco M,Gastaldi M,Cortese A,Alfo...
PubMed ID: 33649809, Nie L,Liu M,Chen J,Wu Q,Li Y,Yi J,Zheng X,Zhang J,Chu C,Yang J.Hydrogen sulfide ...
PubMed ID: 26196122, Inhibition of pulmonary adenoma in diethylnitrosamine-induced rats by Rhizoma pa...
PubMed ID: 28260896, Long-term intravenous administration of carboxylated single-walled carbon nanotu...
PubMed ID: 27575818, Effect of Novel Gasotransmitter hydrogen sulfide on renal fibrosis and connexins...
PubMed ID: 20688607, Effect of norcantharidin on proliferation and invasion of human gallbladder carc...
PubMed ID: 29393353, Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK...
PubMed ID: 27453531, The inhibition of calpains ameliorates vascular restenosis through MMP2/TGF-?1 p...
PubMed ID: 27340562, Inhibition of Zymosan-Induced Inflammatory Factors Expression by ATRA Nanostruct...
PubMed ID: 26870168, MMP-1/2 and TIMP-1/2 expression levels, and the levels of collagenous and elasti...
PubMed ID: 26126526, Acute exacerbations of COPD are associated with significant activation of matrix...
PubMed ID: 28748494, Zhang, B., Shi, Y.Q., Zou, J.J., Chen, X.F., Tang, W., Ye, F., & Liu, Z.M. (2017...
PubMed ID: 24427326, Wu Ty, Zhang Th, Qu Lm, Feng Jp, Tian Ll, Zhang Bh, Li Dd, Sun Yn, Liu M. Int J ...
PubMed ID: 21501651, Qiu Lb, Zhou Y, Wang Q, Yang Ll, Liu Hq, Xu Sl, Qi Yh, Ding Gr, Guo Gz. Toxicolo...

*Showing only the more recent 20. More publications can be found for each product on its corresponding product page