Product Info Summary
SKU: | A01791-1 |
---|---|
Size: | 100 µl |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-TFE3/Transcription Factor E3 Antibody
View all Transcription factor E3 Antibodies
SKU/Catalog Number
A01791-1
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-TFE3/Transcription Factor E3 Antibody (Catalog # A01791-1). Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-TFE3/Transcription Factor E3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01791-1)
Host
Rabbit
Contents
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Peptide sequence around aa.303~307 (L-D-V-Y-S) derived from Human TFE3.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01791-1 is reactive to TFE3 in Human, Mouse, Rat
Applications
A01791-1 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
61521 MW
Background of Transcription factor E3
Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.
Clark J., Lu Y.-J., Sidhar S.K., Parker C., Gill S. Oncogene 15:2233-2239(1997) Weterman M.A.J., Wilbrink M., Proc. Natl. Acad. Sci. U.S.A. 93:15294-15298(1996)
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Predicted MW: 70kd
Western blotting: 1:500~1:1000
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of extracts from 293 cells using TFE3 antibody A01791-1.
Protein Target Info & Infographic
Gene/Protein Information For TFE3 (Source: Uniprot.org, NCBI)
Gene Name
TFE3
Full Name
Transcription factor E3
Weight
61521 MW
Superfamily
MiT/TFE family
Alternative Names
BHLHE33; bHLHe33transcription factor E3; Class E basic helix-loop-helix protein 33; RCCP2; TFEA; transcription factor binding to IGHM enhancer 3; transcription factor E family, member A; Transcription factor for IgH enhancer TFE3 RCCP2, RCCX1, TFEA, bHLHe33 transcription factor binding to IGHM enhancer 3 transcription factor E3|class E basic helix-loop-helix protein 33|transcription factor E family, member A|transcription factor for IgH enhancer|transcription factor for immunoglobulin heavy-chain enhancer 3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TFE3, check out the TFE3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TFE3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TFE3/Transcription Factor E3 Antibody (A01791-1)
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No publications found for A01791-1
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