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Product Info Summary
| SKU: | A00111 |
|---|---|
| Size: | 100μl |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | IHC, WB |
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Product info
Product Name
Anti-RNase III Drosha Antibody
SKU/Catalog Number
A00111
Size
100μl
Form
Liquid
Description
Boster Bio Anti-RNase III Drosha Antibody catalog # A00111. Tested in IHC, WB applications. This antibody reacts with Human, Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-RNase III Drosha Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00111)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from the Internal region of human RNase III Drosha.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A00111 is reactive to Drosha in Human, Mouse
Applications
A00111 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
39 kDa
Calculated molecular weight
159316 MW
Background of Drosha
COX-2, also known as prostaglandin H synthase, was identified less than a decade ago. Its discovery was followed by a period of discovery and drug development to create a “super aspirin” and led to insights into arthritis, Alzheimer's disease, colorectal cancer and regulation of brain and kidney function in search of better treatments for degenerative and inflammatory diseases. Cox-2 is involved in the response of cells to growth factors, tumor promoters, and cytokines that induce its expression. Given its role in synthesizing prostaglandins, Cox-2 is therefore of interest in studying immune response regulation.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB, 1:500-1:2000
IHC-P, 1:100-1:300
Validation Images & Assay Conditions
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Western Blot (WB) analysis of SH-SY5Y K562 HeLa using RNase III Drosha antibody.
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Immunohistochemistry (IHC) analysis of paraffin-embedded Human Kidney, antibody was diluted at 1:200.
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Immunohistochemistry (IHC) analysis of paraffin-embedded Human Brain, antibody was diluted at 1:200.
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Immunohistochemistry (IHC) analysis of paraffin-embedded Human Kidney, antibody was diluted at 1:200.
Protein Target Info & Infographic
Gene/Protein Information For Drosha (Source: Uniprot.org, NCBI)
Gene Name
Drosha
Full Name
Ribonuclease 3
Weight
159316 MW
Superfamily
ribonuclease III family
Alternative Names
drosha, double-stranded RNA-specific endoribonuclease; drosha, ribonuclease type III; EC 3.1.26.3; ETOHI2; nuclear RNase III Drosha; p241; Protein Drosha; putative protein p241 which interacts with transcription factor Sp1; putative ribonuclease III; RANSE3L; ribonuclease 3; Ribonuclease III; ribonuclease III, nuclear; RN3nuclear; RNase III Drosha|1110013A17Rik, AI874853, Etoh, Etohi2, R, Rn3, Rnasen|drosha, ribonuclease type III|ribonuclease 3|RNase III|ethanol induced 2|protein Drosha|ribonuclease III, nuclear
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Drosha, check out the Drosha Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Drosha: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-RNase III Drosha Antibody (A00111)
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No publications found for A00111
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