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Key=store_id
Key=entity_id, value=87395
Key=attribute_set_id, value=4
Key=type_id, value=simple
Key=sku, value=A00818S176
Key=has_options, value=0
Key=required_options, value=0
Key=created_at, value=2020-03-11 06:19:24
Key=updated_at, value=2024-10-19 05:11:19
Key=mst_search_weight, value=0
Key=status, value=Enabled
Key=name, value=Anti-Phospho-RIP2 (S176) RIPK2 Antibody
Key=cj_search_index
Key=publication_count, value=0
Key=qty_in_warehouses
Key=is_recurring, value=Yes
Key=visibility, value=Catalog, Search
Key=tax_class_id, value=Taxable Goods
Key=featured, value=No
Key=featured_image, value=Yes
Key=fb_product, value=
Key=custom_product_page, value=No
Key=free_shipping, value=No
Key=template, value=antibodies
Key=host, value=Rabbit
Key=quantity_and_stock_status
Key=googleshopping_exclude, value=No
Key=yoast_keyword_score, value=-1211
Key=yoast_content_score, value=90
Key=price, value=380.0000
Key=weight, value=1.0000
Key=meta_title, value=Anti-Phospho-RIP2 (S176) RIPK2 Antibody
Key=meta_description, value=Boster Bio Anti-Phospho-RIP2 (S176) RIPK2 Antibody catalog # A00818S176. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse. Supplied as 100ul in Liquid form antibody.
Key=image, value=/a/0/a00788-1-immunohistochemistry-analysis-1.jpg
Key=small_image, value=/a/0/a00788-1-immunohistochemistry-analysis-1.jpg
Key=thumbnail, value=/a/0/a00788-1-immunohistochemistry-analysis-1.jpg
Key=url_key, value=anti-phospho-rip2-s176-ripk2-antibody-a00818s176-boster
Key=url_path, value=anti-collagen-iii-antibody-a00788-1-boster
Key=options_container, value=Block after Info Column
Key=image_label, value=Immunohistochemistry analysis of paraffin-embedded human pancreas tissue, using Collagen III antibody A00788-1.
Key=small_image_label, value=Immunohistochemistry analysis of paraffin-embedded human pancreas tissue, using Collagen III antibody A00788-1.
Key=thumbnail_label, value=Immunohistochemistry analysis of paraffin-embedded human pancreas tissue, using Collagen III antibody A00788-1.
Key=msrp_display_actual_price_type, value=Use config
Key=gift_message_available, value=No
Key=size, value=100ul
Key=protein_name, value=Receptor-interacting serine/threonine-protein kinase 2
Key=gene_full_name, value=Receptor-interacting serine/threonine-protein kinase 2
Key=uniprot_id, value=O43353
Key=applications, value=ELISA, IHC, WB
Key=reactivity, value=Human, Mouse
Key=form, value=Liquid
Key=concentration, value=1 mg/ml
Key=cross_reactivity, value=No cross reactivity with other proteins.
Key=source_company, value=Huafeng (order through China) HF34085, cost 100ul 650RMB
Key=isotype, value=IgG
Key=molecular_weight, value=61195 MW
Key=sample_size_available, value=5ul, free with shipping charge
Key=related_product_skus, value=MA1029,PROTP02461,RP1033
Key=product_category, value=Primary Antibodies
Key=research_category, value=Cytoskeleton/ECM, ECM Proteins, Extracellular Matrix, Mesenchymal Stem Cells, Signal Transduction, Stem Cells
Key=clonality, value=Polyclonal
Key=swatch_image, value=/a/0/a00767-rbpj-primary-antibodies-wb-testing-1.jpg
Key=rating_value, value=100
Key=review_count, value=2
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Key=cj_related_products, value=Inflammatory Disorder:EK0783|FEK0782^Listeriosis:A14413|A05754-2^Septic Shock:PB9010|A00002-2
Key=description, value=Boster Bio Anti-Phospho-RIP2 (S176) RIPK2 Antibody catalog # A00818S176. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse.
Key=short_description, value=Boster Bio Anti-Phospho-RIP2 (S176) RIPK2 Antibody catalog # A00818S176. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse.
Key=meta_keyword, value=Anti-Phospho-RIP2 (S176) RIPK2 Antibody
Key=contents, value=Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Key=gene_name, value=RIPK2
Key=synonyms, value=Receptor-interacting serine/threonine-protein kinase 2;2.7.11.1;CARD-containing interleukin-1 beta-converting enzyme-associated kinase;CARD-containing IL-1 beta ICE-kinase;RIP-like-interacting CLARP kinase;Receptor-interacting protein 2;RIP-2;Tyrosine-protein kinase RIPK2;2.7.10.2;RIPK2;CARDIAK, RICK, RIP2;UNQ277/PRO314/PRO34092;
Key=application_details, value=WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
Key=subcellular_localization, value=Cytoplasm .
Key=tissue_specificity, value=Detected in heart, brain, placenta, lung,
peripheral blood leukocytes, spleen, kidney, testis, prostate,
pancreas and lymph node.
Key=protein_function, value=Serine/threonine/tyrosine kinase that plays an essential
role in modulation of innate and adaptive immune responses. Upon
stimulation by bacterial peptidoglycans, NOD1 and NOD2 are
activated, oligomerize and recruit RIPK2 through CARD-CARD
domains. Contributes to the tyrosine phosphorylation of the
guanine exchange factor ARHGEF2 through Src tyrosine kinase
leading to NF-kappaB activation by NOD2. Once recruited, RIPK2
autophosphorylates and undergoes 'Lys-63'-linked
polyubiquitination by E3 ubiquitin ligases XIAP, BIRC2 and BIRC3.
The polyubiquitinated protein mediates the recruitment of
MAP3K7/TAK1 to IKBKG/NEMO and induces 'Lys-63'-linked
polyubiquitination of IKBKG/NEMO and subsequent activation of
IKBKB/IKKB. In turn, NF-kappa-B is released from NF-kappa-B
inhibitors and translocates into the nucleus where it activates
the transcription of hundreds of genes involved in immune
response, growth control, or protection against apoptosis. Plays
also a role during engagement of the T-cell receptor (TCR) in
promoting BCL10 phosphorylation and subsequent NF-kappa-B
activation.
Key=application_notes, value=Anti-PPAR alpha Antibody has been tested in ELISA, Western Blot, Immunohistochemistry, and Immunofluorescence. Expect a single band approximately 52 kDa in size corresponding to PPAR alpha by western blot in the appropriate tissue or cell lysate. A 1:200 dilution is suggested for Immunohistochemistry. Specific conditions for reactivity should be optimized by the end user.
Key=competitor_equivalent_skus, value=sc 59849|sc 5582|sc 74418|sc 74417|sc 6017|sc 65646|sc 65645|sc 6016|sc 28888|sc 8781|sc 271249|sc 8780 R|sc 514601
Key=immunogen, value=The antiserum was produced against synthesized peptide derived from human RIPK2 around the phosphorylation site of Ser176. AA range:146-195
Key=purification, value=The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Key=storage, value=Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Key=options
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Key=tier_price_changed
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Anti-Phospho-RIP2 (S176) RIPK2 Antibody
RIPK2 antibody
Boster Bio Anti-Phospho-RIP2 (S176) RIPK2 Antibody catalog # A00818S176. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse.
No images for this product yet
Product Info Summary
SKU:
A00818S176
Size:
100ul
Reactive Species:
Human, Mouse
Host:
Rabbit
Application:
ELISA, IHC, WB
Product Name
Anti-Phospho-RIP2 (S176) RIPK2 Antibody
View all RIPK2 Antibodies
SKU/Catalog Number
A00818S176
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Phospho-RIP2 (S176) RIPK2 Antibody catalog # A00818S176. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Phospho-RIP2 (S176) RIPK2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00818S176)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
The antiserum was produced against synthesized peptide derived from human RIPK2 around the phosphorylation site of Ser176. AA range:146-195
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A00818S176 is reactive to RIPK2 in Human, Mouse
Reconstitution
Calculated molecular weight
61195 MW
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
View more details
Applications
A00818S176 is guaranteed for ELISA, IHC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:40000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Gene/Protein Information For RIPK2 (Source: Uniprot.org, NCBI)
Full Name
Receptor-interacting serine/threonine-protein kinase 2
Superfamily
protein kinase superfamily
Alternative Names
Receptor-interacting serine/threonine-protein kinase 2;2.7.11.1;CARD-containing interleukin-1 beta-converting enzyme-associated kinase;CARD-containing IL-1 beta ICE-kinase;RIP-like-interacting CLARP kinase;Receptor-interacting protein 2;RIP-2;Tyrosine-protein kinase RIPK2;2.7.10.2;RIPK2;CARDIAK, RICK, RIP2;UNQ277/PRO314/PRO34092;
RIPK2 CARD3, CARDIAK, CCK, GIG30, RICK, RIP2 receptor interacting serine/threonine kinase 2 receptor-interacting serine/threonine-protein kinase 2|CARD-carrying kinase|CARD-containing IL-1 beta ICE-kinase|CARD-containing interleukin-1 beta-converting enzyme (ICE)-associated kinase|RIP-2|growth-inhibiting gene 30|receptor-interacting protein (RIP)-like interacting caspase-like apoptosis regulatory protein (CLARP) kinase|receptor-interacting protein 2|tyrosine-protein kinase RIPK2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".
For more info on RIPK2, check out the RIPK2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for RIPK2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected] .
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