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Key=meta_description, value=Boster Bio Anti-Phospho-RIP2 (S176) RIPK2 Antibody catalog # A00818S176. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse. Supplied as 100ul in Liquid form antibody.
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Key=url_path, value=anti-collagen-iii-antibody-a00788-1-boster
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Key=image_label, value=Immunohistochemistry analysis of paraffin-embedded human pancreas tissue, using Collagen III antibody A00788-1.
Key=small_image_label, value=Immunohistochemistry analysis of paraffin-embedded human pancreas tissue, using Collagen III antibody A00788-1.
Key=thumbnail_label, value=Immunohistochemistry analysis of paraffin-embedded human pancreas tissue, using Collagen III antibody A00788-1.
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Key=cross_reactivity, value=No cross reactivity with other proteins.
Key=source_company, value=Huafeng (order through China) HF34085, cost 100ul 650RMB
Key=isotype, value=IgG
Key=molecular_weight, value=61195 MW
Key=sample_size_available, value=5ul, free with shipping charge
Key=related_product_skus, value=MA1029,PROTP02461,RP1033
Key=product_category, value=Primary Antibodies
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Key=description, value=Boster Bio Anti-Phospho-RIP2 (S176) RIPK2 Antibody catalog # A00818S176. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse.
Key=short_description, value=Boster Bio Anti-Phospho-RIP2 (S176) RIPK2 Antibody catalog # A00818S176. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse.
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Key=contents, value=Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Key=gene_name, value=RIPK2
Key=synonyms, value=Receptor-interacting serine/threonine-protein kinase 2;2.7.11.1;CARD-containing interleukin-1 beta-converting enzyme-associated kinase;CARD-containing IL-1 beta ICE-kinase;RIP-like-interacting CLARP kinase;Receptor-interacting protein 2;RIP-2;Tyrosine-protein kinase RIPK2;2.7.10.2;RIPK2;CARDIAK, RICK, RIP2;UNQ277/PRO314/PRO34092;
Key=application_details, value=WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
Key=subcellular_localization, value=Cytoplasm .
Key=tissue_specificity, value=Detected in heart, brain, placenta, lung, peripheral blood leukocytes, spleen, kidney, testis, prostate, pancreas and lymph node.
Key=protein_function, value=Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. Contributes to the tyrosine phosphorylation of the guanine exchange factor ARHGEF2 through Src tyrosine kinase leading to NF-kappaB activation by NOD2. Once recruited, RIPK2 autophosphorylates and undergoes 'Lys-63'-linked polyubiquitination by E3 ubiquitin ligases XIAP, BIRC2 and BIRC3. The polyubiquitinated protein mediates the recruitment of MAP3K7/TAK1 to IKBKG/NEMO and induces 'Lys-63'-linked polyubiquitination of IKBKG/NEMO and subsequent activation of IKBKB/IKKB. In turn, NF-kappa-B is released from NF-kappa-B inhibitors and translocates into the nucleus where it activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis. Plays also a role during engagement of the T-cell receptor (TCR) in promoting BCL10 phosphorylation and subsequent NF-kappa-B activation.
Key=application_notes, value=Anti-PPAR alpha Antibody has been tested in ELISA, Western Blot, Immunohistochemistry, and Immunofluorescence. Expect a single band approximately 52 kDa in size corresponding to PPAR alpha by western blot in the appropriate tissue or cell lysate. A 1:200 dilution is suggested for Immunohistochemistry. Specific conditions for reactivity should be optimized by the end user.
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Key=immunogen, value=The antiserum was produced against synthesized peptide derived from human RIPK2 around the phosphorylation site of Ser176. AA range:146-195
Key=purification, value=The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Key=storage, value=Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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Anti-Phospho-RIP2 (S176) RIPK2 Antibody

RIPK2 antibody

Boster Bio Anti-Phospho-RIP2 (S176) RIPK2 Antibody catalog # A00818S176. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse.

Product Info Summary

SKU: A00818S176
Size: 100ul
Reactive Species: Human, Mouse
Host: Rabbit
Application: ELISA, IHC, WB

Product Name

Anti-Phospho-RIP2 (S176) RIPK2 Antibody

View all RIPK2 Antibodies

SKU/Catalog Number

A00818S176

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Phospho-RIP2 (S176) RIPK2 Antibody catalog # A00818S176. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Phospho-RIP2 (S176) RIPK2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00818S176)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human RIPK2 around the phosphorylation site of Ser176. AA range:146-195

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A00818S176 is reactive to RIPK2 in Human, Mouse

Reconstitution

Calculated molecular weight

61195 MW

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Applications

A00818S176 is guaranteed for ELISA, IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For RIPK2 (Source: Uniprot.org, NCBI)

Gene Name

RIPK2

Full Name

Receptor-interacting serine/threonine-protein kinase 2

Weight

61195 MW

Superfamily

protein kinase superfamily

Alternative Names

Receptor-interacting serine/threonine-protein kinase 2;2.7.11.1;CARD-containing interleukin-1 beta-converting enzyme-associated kinase;CARD-containing IL-1 beta ICE-kinase;RIP-like-interacting CLARP kinase;Receptor-interacting protein 2;RIP-2;Tyrosine-protein kinase RIPK2;2.7.10.2;RIPK2;CARDIAK, RICK, RIP2;UNQ277/PRO314/PRO34092; RIPK2 CARD3, CARDIAK, CCK, GIG30, RICK, RIP2 receptor interacting serine/threonine kinase 2 receptor-interacting serine/threonine-protein kinase 2|CARD-carrying kinase|CARD-containing IL-1 beta ICE-kinase|CARD-containing interleukin-1 beta-converting enzyme (ICE)-associated kinase|RIP-2|growth-inhibiting gene 30|receptor-interacting protein (RIP)-like interacting caspase-like apoptosis regulatory protein (CLARP) kinase|receptor-interacting protein 2|tyrosine-protein kinase RIPK2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on RIPK2, check out the RIPK2 Infographic

RIPK2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for RIPK2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A00818S176-100ul

100ul

$380

Free Secondary Antibody

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A00818S176
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$380.00

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