Data

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Key=store_id
Key=entity_id, value=1425
Key=attribute_set_id, value=4
Key=type_id, value=simple
Key=sku, value=PA1861
Key=has_options, value=1
Key=required_options, value=1
Key=created_at, value=2014-05-08 15:19:06
Key=updated_at, value=2024-10-19 05:03:08
Key=mst_search_weight, value=0
Key=status, value=Enabled
Key=name, value=Anti-RIP2/RIPK2 Antibody Picoband®
Key=cj_search_index
Key=publication_count, value=0
Key=qty_in_warehouses
Key=is_recurring, value=No
Key=visibility, value=Catalog, Search
Key=tax_class_id, value=Taxable Goods
Key=featured, value=No
Key=featured_image, value=Yes
Key=fb_product, value=
Key=custom_product_page, value=No
Key=free_shipping, value=No
Key=template, value=antibodies
Key=host, value=Rabbit
Key=quantity_and_stock_status
Key=googleshopping_exclude, value=No
Key=yoast_keyword_score, value=-1529
Key=yoast_content_score, value=30
Key=badge, value=free-antibody-validation
Key=price, value=370.0000
Key=weight, value=1.0000
Key=meta_title, value=Anti-RIP2/RIPK2 Antibody PA1861
Key=meta_description, value=Boster Bio Anti-RIP2/RIPK2 Antibody catalog # PA1861. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. Supplied as 100μg/vial in Lyophilized form antibody.
Key=image, value=/p/a/pa1861-1.jpg
Key=small_image, value=/p/a/pa1861-1.jpg
Key=thumbnail, value=/p/a/pa1861-1.jpg
Key=url_key, value=anti-rip2-antibody-pa1861-boster
Key=url_path, value=anti-rip2-antibody-pa1861-boster
Key=options_container, value=Product Info Column
Key=image_label, value=Anti-RIP2 antibody, PA1861, Western blotting
Lane 1: A549 Cell Lysate
Lane 2: HELA Cell Lysate
Lane 3: PANC Cell Lysate
Lane 4: COLO320 Cell Lysate

Key=small_image_label, value=Anti-RIP2 antibody, PA1861, Western blotting
Lane 1: A549 Cell Lysate
Lane 2: HELA Cell Lysate
Lane 3: PANC Cell Lysate
Lane 4: COLO320 Cell Lysate

Key=thumbnail_label, value=Anti-RIP2 antibody, PA1861, Western blotting
Lane 1: A549 Cell Lysate
Lane 2: HELA Cell Lysate
Lane 3: PANC Cell Lysate
Lane 4: COLO320 Cell Lysate

Key=msrp_display_actual_price_type, value=
Key=gift_message_available, value=No
Key=size, value=100 μg/vial
Key=protein_name, value=Receptor-interacting serine/threonine-protein kinase 2
Key=gene_full_name, value=Receptor-interacting serine/threonine-protein kinase 2
Key=uniprot_id, value=O43353
Key=reconstitution, value=Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Key=sensitivity
Key=applications, value=WB
Key=reactivity, value=Human, Mouse, Rat
Key=form, value=Lyophilized
Key=concentration, value=Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Key=cross_reactivity, value=No cross-reactivity with other proteins
Key=recommended_detection_systems, value=Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.
Key=predicted_reactivity
Key=source_company, value=Boster PA1861
Key=isotype, value=Rabbit IgG
Key=molecular_weight, value=61195 MW
Key=sample_size_available, value=30ug for $99, contact us for details
Key=related_product_skus, value=B0001-5,AR1156,AR0146
Key=product_category, value=Primary Antibodies
Key=research_category, value=Apoptosis, Cancer, Caspases, Cell Biology, Cell Death, Immunology, Innate Immunity, Intracellular, Invasion/Microenvironment, Kinases, Metabolism, Obesity, Protein Phosphorylation, Receptors, Ser/Thr Kinases, Signal Transduction, TLR Signaling
Key=clonality, value=Polyclonal
Key=swatch_image, value=/e/k/ek0671_1.png
Key=rating_value, value=98.5
Key=review_count, value=10
Key=phospho_site
Key=mp_exclude_sitemap, value=Yes
Key=yoast_focus_keyword, value=CD68 antibody
Key=yoast_facebook_image, value=/p/a/pa1787-2-hexa-primary-antibodies-wb-testing-1_1.jpg
Key=yoast_twitter_image, value=/p/a/pa1787-2-hexa-primary-antibodies-wb-testing-1_1.jpg
Key=cj_related_products, value=Inflammatory Disorder:A00651-4|A00651-5^Listeriosis:A05754-2|A05754-3^Septic Shock:R00002-1
Key=description, value=Boster Bio Anti-RIP2/RIPK2 Antibody catalog # PA1861. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=short_description, value=Boster Bio Anti-RIP2/RIPK2 Antibody catalog # PA1861. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=meta_keyword, value=Anti-RIP2/RIPK2 Antibody
Key=contents, value=Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Key=background, value=RIPK2 (Receptor-interacting serine/threonine-protein kinase 2), also known as CARD3, CARDIAK, RICK, RIP2, is an enzyme that in humans is encoded by the RIPK2 gene. It has 540-amino acid protein in length. Northern blot analysis revealed that RICK is expressed in various human tissues as 2.5- and 1.8-kb mRNAs that differ due to alternative polyadenylation. RICK is a novel kinase that may regulate apoptosis induced by the FAS receptor pathway. This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappa B and inducer of apoptosis in response to various stimuli, CARDIAK (CARD-containing ICE-associated kinase) specifically interacted with the CARD of ICE/caspase-1, and this interaction correlated with the processing of pro-caspase-1 and the formation of the active caspase-1 p20 subunit.
Key=gene_name, value=RIPK2
Key=synonyms, value=Receptor-interacting serine/threonine-protein kinase 2;2.7.11.1;CARD-containing interleukin-1 beta-converting enzyme-associated kinase;CARD-containing IL-1 beta ICE-kinase;RIP-like-interacting CLARP kinase;Receptor-interacting protein 2;RIP-2;Tyrosine-protein kinase RIPK2;2.7.10.2;RIPK2;CARDIAK, RICK, RIP2;UNQ277/PRO314/PRO34092;
Key=application_details, value=Western blot, 0.1-0.5μg/ml, Human, Rat, Mouse

Key=subcellular_localization, value= Cytoplasm .
Key=sequence_similarities, value=Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
Key=tissue_specificity, value= Detected in heart, brain, placenta, lung, peripheral blood leukocytes, spleen, kidney, testis, prostate, pancreas and lymph node.
Key=application_notes, value=Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Key=competitor_equivalent_skus, value=sc 136059|sc 161184|sc 166765|sc 22763|sc 8610|sc 8611
Key=immunogen, value=A synthetic peptide corresponding to a sequence at the C-terminus of human RIP2, different from the related rat and mouse sequences by one amino acid.
Key=purification, value=Immunogen affinity purified.
Key=storage, value=Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Key=custom_attribute_1, value=61 kDa
Key=custom_attribute_2, value=WB: A549 Whole Cell, HELA Whole Cell, PANC Whole Cell, COLO320 Whole Cell
Key=custom_attribute_3, value=BA3824-2
Key=protein_function, value= Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. Contributes to the tyrosine phosphorylation of the guanine exchange factor ARHGEF2 through Src tyrosine kinase leading to NF-kappaB activation by NOD2. Once recruited, RIPK2 autophosphorylates and undergoes 'Lys-63'-linked polyubiquitination by E3 ubiquitin ligases XIAP, BIRC2 and BIRC3. The polyubiquitinated protein mediates the recruitment of MAP3K7/TAK1 to IKBKG/NEMO and induces 'Lys-63'-linked polyubiquitination of IKBKG/NEMO and subsequent activation of IKBKB/IKKB. In turn, NF-kappa-B is released from NF-kappa-B inhibitors and translocates into the nucleus where it activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis. Plays also a role during engagement of the T-cell receptor (TCR) in promoting BCL10 phosphorylation and subsequent NF-kappa-B activation. .
Key=options
Key=media_gallery
Key=extension_attributes
Key=tier_price
Key=tier_price_changed
Key=category_ids
Key=is_salable
Key=website_ids
Key=request_path
Key=rating_summary
Key=_cache_instance_store_filter
Key=media_gallery_images