Anti-Ms CD26 Purified Dpp4 Monoclonal Antibody

Product Name

Anti-Ms CD26 Purified Dpp4 Monoclonal Antibody

View all DPP4 Antibodies

SKU/Catalog Number

M00597-1

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Ms CD26 Purified Dpp4 Monoclonal Antibody (Catalog# M00597-1). Tested in IP, Flow Cytometry, IHC-F application(s). This antibody reacts with Mouse.

Storage & Handling

Store at 2-8°C. Do not freeze.

Cite This Product

Anti-Ms CD26 Purified Dpp4 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00597-1)

Host

Rat

Contents

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Clonality

Monoclonal

Clone Number

H194-112

Isotype

Rat IgG2a kappa

Immunogen

BALB/c thymocytes. The rat monoclonal antibody H194-112 recognizes an extracellular epitope of CD26, a 110 kDa type II membrane glycoprotein, which is a peptidase expressed on mature thymocytes, T cells (especially activated), B cells, NK cells and macrophages.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M00597-1 is reactive to DPP4 in Mouse

Reconstitution

Observed Molecular Weight

19 kDa

Calculated molecular weight

87437 MW

Background of DPP4

CD26, also known as dipeptidyl peptidase IV (DPP-IV), is a homodimeric cell surface serine peptidase that degradates IFN-gamma-induced cytokines, acts as a T cell costimulatory molecule, and participates in multiple immunopathological roles in leukocyte homing and inflammation. Alterations in its peptidase activity are characteristic of malignant transformation. The enzymatic activity increases dramatically with tumour grade and severity. CD26 is expressed in various blood cell types, but also e.g. in cells that are histogenetically related to activated fibroblasts. Alterations in CD26 density have been reported on circulating monocytes and CD4+ T cells during rheumatoid arthritis and systemic lupus erythematosus.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

M00597-1 is guaranteed for Flow Cytometry, IP, IHC-F Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Flow cytometry: 1-4 μg/ml.

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For DPP4 (Source: Uniprot.org, NCBI)

Alternative Names

DPP4, TP103, ADCP-2, ADABP DPP4 ADABP, ADCP2, CD26, DPPIV, TP103 dipeptidyl peptidase 4 dipeptidyl peptidase 4|ADCP-2|DPP IV|Gly-Pro naphthylamidase|Post-proline dipeptidyl aminopeptidase IV|T-cell activation CD26|Xaa-Pro-dipeptidylaminopeptidase|adenosine deaminase complexing protein 2|dipeptidyl peptidase IV|dipeptidylpeptidase 4|dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2)

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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