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Key=entity_id, value=76873
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Key=type_id, value=simple
Key=sku, value=M00227-Biotin
Key=has_options, value=1
Key=required_options, value=1
Key=created_at, value=2020-03-11 06:18:51
Key=updated_at, value=2024-09-26 01:03:57
Key=mst_search_weight, value=0
Key=status, value=Enabled
Key=name, value=Anti-GAPDH Monoclonal Antibody [12D3D5] (biotin)
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Key=is_recurring, value=No
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Key=conjugate
Key=featured, value=No
Key=featured_image, value=Yes
Key=fb_product, value=
Key=custom_product_page, value=No
Key=free_shipping, value=No
Key=template, value=antibodies
Key=host, value=Mouse
Key=quantity_and_stock_status
Key=googleshopping_exclude, value=No
Key=yoast_keyword_score, value=-1369
Key=yoast_content_score, value=60
Key=price, value=449.0000
Key=weight, value=1.0000
Key=meta_title, value=Anti-GAPDH Monoclonal Antibody [12D3D5] (biotin)
Key=meta_description, value=Boster Bio Anti-GAPDH Monoclonal Antibody [12D3D5] (biotin) (Catalog # M00227-Biotin). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat, Rabbit. Supplied as 0.1 mg in Liquid form antibody.
Key=image, value=no_selection
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Key=url_key, value=anti-gapdh-monoclonal-antibody-12d3d5-biotin-m00227-biotin-boster
Key=url_path, value=anti-il-8-antibody-a00423-boster
Key=options_container, value=Block after Info Column
Key=msrp_display_actual_price_type, value=Use config
Key=gift_message_available, value=No
Key=size, value=0.1 mg
Key=protein_name, value=Glyceraldehyde-3-phosphate dehydrogenase
Key=gene_full_name, value=Glyceraldehyde-3-phosphate dehydrogenase
Key=uniprot_id, value=P04406
Key=sensitivity
Key=applications, value=ELISA, WB
Key=reactivity, value=Human, Mouse, Rabbit, Rat
Key=form, value=Liquid
Key=concentration, value=1 mg/mL
Key=cross_reactivity, value=Biotin-GAPDH antibody is human, mouse, rat, and rabbit reactive.
Key=clone_number, value=Clone: 12D3D5
Key=predicted_reactivity, value=Mouse, Rat
Key=source_company, value=Prosci PM-7569-biotin; Cost: 249
Key=isotype, value=IgG
Key=molecular_weight, value=36053 MW
Key=sample_size_available, value=25ug for $99, contact us for details
Key=related_product_skus, value=EK0413,PB9621,PROTP10145,PROTP10145-1,PROTP10145-2,PROTP10145-3,PROTP19874,PROTP26894,PROTP41324,PROTP67813
Key=product_category, value=Primary Antibodies, Monoclonal Antibodies
Key=research_category, value=Neuroscience, Signal Transduction, Homeostasis
Key=clonality, value=Monoclonal
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Key=rating_value, value=100
Key=review_count, value=6
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Key=cj_related_products, value=Loading Controls:M00256-1^Nuclear Receptors, Coactivators and Corepressors:A00227|A00227-1|M00227|A00227-Biotin|A06060-2
Key=description, value=Boster Bio Anti-GAPDH Monoclonal Antibody [12D3D5] (biotin) (Catalog # M00227-Biotin). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat, Rabbit.
Key=short_description, value=Boster Bio Anti-GAPDH Monoclonal Antibody [12D3D5] (biotin) (Catalog # M00227-Biotin). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat, Rabbit.
Key=meta_keyword, value=Anti-GAPDH Monoclonal Antibody [12D3D5] (biotin)
Key=contents, value=Biotin-GAPDH antibody is supplied in PBS containing 1% BSA and 0.02% sodium azide.
Key=background, value=Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD), an important energy-yielding step in carbohydrate metabolism. It also is involved in a number of cellular processes such as membrane fusion, phosphotransferase activity, DNA replication and repair, and nuclear RNA export (1). GAPDH also plays a role in different pathologies such as cancer progression, apoptosis, and neuronal diseases such as Alzheimer's and Huntington's disease (2). GAPDH is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots.
Key=gene_name, value=GAPDH
Key=synonyms, value=Glyceraldehyde-3-phosphate dehydrogenase, G3PDH, GAPD
Key=application_details, value=Biotin-GAPDH antibody can be used for detection of GAPDH by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in human, mouse, and rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Key=subcellular_localization, value=Cytoplasm, cytosol
Key=tissue_specificity, value=Thymus.
Key=protein_function, value=Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D- glyceroyl phosphate. Component of the GAIT (gamma interferon- activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.
Key=application_notes
Key=description_before_attributes
Key=competitor_equivalent_skus, value=sc 25342|sc 55462|sc 7165|sc 4600|sc 73321|sc 7922|sc 1269|sc 376750|sc 8427|sc 7302|sc 52870|sc 101499|sc 32817|sc 71367
Key=immunogen, value=Biotin-GAPDH antibody was raised against a 16 amino acid peptide near the carboxy terminus of human GAPDH.
Key=purification, value=Biotin-GAPDH antibody is Protein A purified.
Key=storage, value=Biotin-GAPDH antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Key=custom_attribute_1, value=68 kDa
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