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- Table of Contents
246 Citations 16 Q&As
161 Citations 4 Q&As
150 Citations 17 Q&As
153 Citations 16 Q&As
132 Citations 16 Q&As
127 Citations 16 Q&As
50 Citations
Facts about Glyceraldehyde-3-phosphate dehydrogenase.
Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Facilitates the CHP1-dependent microtubule and membrane associations through its capacity to stimulate the binding of CHP1 into microtubules (By similarity).
Human | |
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Gene Name: | GAPDH |
Uniprot: | P04406 |
Entrez: | 2597 |
Belongs to: |
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glyceraldehyde-3-phosphate dehydrogenase family |
1D4 GAPDH; aging-associated gene 9 protein; Cytoplasm Marker; EC 1.2.1; EC 1.2.1.12; EC 2.6.99.-; G3PD; G3PD; G3PDH; GAPD; GAPDH; GAPDPeptidyl-cysteine S-nitrosylase GAPDH; glyceraldehyde 3-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase; MGC102544; MGC102546; MGC103190; MGC103191; MGC105239; MGC127711; MGC88685; OCAS, p38; OCT1 coactivator in S phase; Peptidyl-cysteine S-nitrosylase GAPDH
Mass (kDA):
36.053 kDA
Human | |
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Location: | 12p13.31 |
Sequence: | 12; NC_000012.12 (6534517..6538371) |
Cytoplasm, cytosol. Nucleus. Cytoplasm, perinuclear region. Membrane. Cytoplasm, cytoskeleton. Translocates to the nucleus following S-nitrosylation and interaction with SIAH1, which contains a nuclear localization signal (By similarity). Postnuclear and Perinuclear regions.
PMID: 6096136 by Hanauer A., et al. The glyceraldehyde 3 phosphate dehydrogenase gene family: structure of a human cDNA and of an X chromosome linked pseudogene; amazing complexity of the gene family in mouse.
PMID: 6096821 by Arcari P., et al. The complete sequence of a full length cDNA for human liver glyceraldehyde-3-phosphate dehydrogenase: evidence for multiple mRNA species.
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page