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Product Info Summary
| SKU: | M00961-3 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | ELISA |
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Product info
Product Name
Anti-Cystatin C/CST3 Antibody (monoclonal, 8H7)
View all Cystatin C Antibodies
SKU/Catalog Number
M00961-3
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-Cystatin C/CST3 Antibody (monoclonal, 8H7) catalog # M00961-3. Tested in ELISA applications. This antibody reacts with Human.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Cystatin C/CST3 Antibody (monoclonal, 8H7) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00961-3)
Host
Mouse
Contents
Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Clonality
Monoclonal
Clone Number
8H7
Isotype
Mouse IgG1
Immunogen
E. coli-derived human Cystatin C recombinant protein (Position: K31-A146).
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins.
Reactive Species
M00961-3 is reactive to CST3 in Human
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500μg/ml.
Observed Molecular Weight
15 kDa
Calculated molecular weight
15.799kDa
Background of Cystatin C
Cystatin C or cystatin 3, a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid, such as Alzheimer's disease. In humans, all cells with a nucleus (cell core containing the DNA) produce cystatin C as a chain of 120 amino acids. It is found in virtually all tissues and body fluids. It is a potent inhibitor of lysosomal proteinases (enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases (it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes). Cystatin C belongs to the type 2 cystatin gene family.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M00961-3 is guaranteed for ELISA Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ELISA (Cap), 1-5μg/ml
Validation Images & Assay Conditions
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Figure 1. Sandwich ELISA - Recombinant human Cystatin C/CST3 protein standard curve.
Use in combination with reagents from Human Cystatin C/CST3 ELISA Kit EZ-Set (DIY Antibody Pairs) (EZ0678).
Protein Target Info & Infographic
Gene/Protein Information For CST3 (Source: Uniprot.org, NCBI)
Gene Name
CST3
Full Name
Cystatin-C
Weight
15.799kDa
Superfamily
cystatin family
Alternative Names
Nuclear factor 1 A-type; NF1-A; Nuclear factor 1/A; CCAAT-box-binding transcription factor; CTF; Nuclear factor I/A; NF-I/A; NFI-A; TGGCA-binding protein; NFIA; KIAA1439 CST3 ARMD11, HEL-S-2 cystatin C cystatin-C|bA218C14.4 (cystatin C)|cystatin 3|epididymis secretory protein Li 2|gamma-trace|neuroendocrine basic polypeptide|post-gamma-globulin
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CST3, check out the CST3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CST3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Cystatin C/CST3 Antibody (monoclonal, 8H7) (M00961-3)
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