Anti-CUG-BP1/2 (K95) CELF1 Antibody

Product Name

Anti-CUG-BP1/2 (K95) CELF1 Antibody

View all CUGBP1/CELF1 Antibodies

SKU/Catalog Number

A02163

Size

100ul

Form

Liquid

Description

Boster Bio Anti-CUG-BP1/2 (K95) CELF1 Antibody catalog # A02163. Tested in IHC applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-CUG-BP1/2 (K95) CELF1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02163)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human Rad17 around the phosphorylation site of S646.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A02163 is reactive to CELF1 in Human, Mouse, Rat

Applications

A02163 is guaranteed for IHC Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

52063 MW

Background of CUGBP1/CELF1

Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1 and BHLHE40/DEC1, which decreases its transcriptional repression activity. Deconjugates SUMO1 from CLOCK, which decreases its transcriptional activation activity.

Taihei Yamaguchi, Mol. Cell. Biol., Jun 2005; 25: 5171 - 5182.
Jinke Cheng, Mol. Cell. Biol., Jul 2004; 24: 6021 - 6028.
Molly A. Brewer, AACR Meeting Abstracts, Mar 2004; 2004: 1006.
Imke M. Veltman, Hum. Mol. Genet., Jul 2005; 14: 1955 - 1963.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

IHC: 1:50-1:200

Validation Images & Assay Conditions

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Figure 1. Immunohistochemistry validation of CELF1 using Anti-CUG-BP1/2 (K95) CELF1 Antibody (A02163).

Immunohistochemistry (IHC) analyzes of CUG-BP1/2 (K95) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.
For more protocol information of IHC

Gene/Protein Information For CELF1 (Source: Uniprot.org, NCBI)

Alternative Names

BRUNOL2; BRUNOL250 kDa nuclear polyadenylated RNA-binding protein; bruno-like 2; Bruno-like protein 2; CELF1; CUG RNA-binding protein; CUG triplet repeat, RNA binding protein 1; CUG triplet repeat, RNA-binding protein 1; CUG-BP- and ETR-3-like factor 1; CUGBP Elav-like family member 1; CUG-BP; CUGBP, Elav-like family member 1; CUGBP1; CUG-BP1; CUGBP1CUG triplet repeat RNA-binding protein 1; CUGBPCELF-1; D2Wsu101e; Deadenylation factor CUG-BP; EDEN-BP homolog; EDEN-BP; embryo deadenylation element binding protein; Embryo deadenylation element-binding protein homolog; HNAB50; NAB50; NAB50CUG-BP1 CELF1 BRUNOL2, CUG-BP, CUGBP, CUGBP1, EDEN-BP, NAB50, NAPOR, hNab50 CUGBP Elav-like family member 1 CUGBP Elav-like family member 1|50 kDa nuclear polyadenylated RNA-binding protein|CUG RNA-binding protein|CUG triplet repeat RNA-binding protein 1|CUG-BP- and ETR-3-like factor 1|EDEN-BP homolog|RNA-binding protein BRUNOL-2|bruno-like 2|bruno-like protein 2|deadenylation factor CUG-BP|embryo deadenylation element binding protein|embryo deadenylation element-binding protein homolog|nuclear polyadenylated RNA-binding protein, 50-kD

For more info on CELF1, check out the CELF1 Infographic

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In this infographic, you will see the following information for CELF1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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