Anti-Clusterin (human) Monoclonal Antibody (CLI-9)

Product Name

Anti-Clusterin (human) Monoclonal Antibody (CLI-9)

View all Clusterin/APOJ Antibodies

SKU/Catalog Number

M00590

Size

100µg

Form

Liquid

Description

Boster Bio Anti-Clusterin (human) Monoclonal Antibody (CLI-9) (Catalog# M00590). Tested in ICC, IHC-F, IHC-P, IP, WB application(s). This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Clusterin (human) Monoclonal Antibody (CLI-9) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00590)

Host

Mouse

Contents

Liquid. In PBS containing 0.02% sodium azide.

Clonality

Monoclonal

Clone Number

CLI-9

Isotype

IgG1

Immunogen

Purified human clusterin (TRPM-2)

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

Does not cross-react with primate, avian or amphibian GR.

Reactive Species

M00590 is reactive to CLU in Human

Reconstitution

Reconstitute with distilled water.

Calculated molecular weight

87058 MW

Background of Clusterin/APOJ

Reacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain). It associates with the IIb-chain (CD41) to form the GpIIb/GpIIIa complex (CD41/CD61).The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor, soluble fibrinogen, fibronectin, vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 is implicated in tumor metastasis and adenoviral infection. The antibody detects platelets in smears of blood and bone marrow, as well as megakaryocytes in frozen sections and cell smears. The antibody is useful for classification of megakaryoblastic leukemia.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

M00590 is guaranteed for IP, IHC-P, IHC-F, ICC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western Blot (1:2,000)
Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application.

Validation Images & Assay Conditions

Gene/Protein Information For CLU (Source: Uniprot.org, NCBI)

Alternative Names

Integrin beta-3;Platelet membrane glycoprotein IIIa;GPIIIa;CD61;ITGB3;GP3A; CLU AAG4, APO-J, APOJ, CLI1, CLU2, KUB1, NA1/NA2, SGP-2, SGP2, SP-40, TRPM-2, TRPM2, CLU clusterin clusterin|aging-associated protein 4|apolipoprotein J|complement cytolysis inhibitor|complement lysis inhibitor|complement-associated protein SP-40,40|epididymis secretory sperm binding protein|ku70-binding protein 1|sulfated glycoprotein 2|testosterone-repressed prostate message 2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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