Anti-CHI3L1 Antibody Picoband®

Product Name

Anti-CHI3L1 Antibody Picoband®

View all Chitinase 3-like 1 Antibodies

SKU/Catalog Number

A01283-1

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-CHI3L1 Antibody Picoband® catalog # A01283-1. Tested in ELISA, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-CHI3L1 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01283-1)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E. coli-derived mouse CHI3L1 recombinant protein (Position: Y30-K262).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A01283-1 is reactive to Chi3l1 in Mouse

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

43 kDa

Calculated molecular weight

42.625kDa

Background of Chitinase 3-like 1

Chitinase-3-like protein 1 (CHI3L1), also known as YKL-40, is a secreted glycoprotein that is approximately 40kDa in size that in humans is encoded by the CHI3L1 gene. This gene is mapped to 1q32.1. Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A01283-1 is guaranteed for ELISA, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml
ELISA, 0.1-0.5μg/ml

Positive Control

WB: mouse RAW2647 whole cell, mouse HEPA1-6 whole cell

Validation Images & Assay Conditions

Gene/Protein Information For Chi3l1 (Source: Uniprot.org, NCBI)

Alternative Names

Chitinase-3-like protein 1; BRP39 protein; Breast regression protein 39; Cartilage glycoprotein 39; CGP-39; GP-39; Chi3l1; Brp39, Chil1; CHI3L1 ASRT7, CGP-39, GP-39, GP39, HC-gp39, HCGP-3P, YK-40, YKL-40, YKL40, YYL-40, hCGP-39 chitinase 3 like 1 chitinase-3-like protein 1|39 kDa synovial protein|cartilage glycoprotein 39|chitinase 3-like 1 (cartilage glycoprotein-39)

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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