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Product Info Summary
| SKU: | M00602-1 |
|---|---|
| Size: | 100 μl |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-CD68/Sr D1 Rabbit Monoclonal Antibody
View all CD68/SR-D1 Antibodies
SKU/Catalog Number
M00602-1
Size
100 μl
Form
Liquid
Description
Boster Bio Anti-CD68/Sr D1 Rabbit Monoclonal Antibody catalog # M00602-1. Tested in WB application. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-CD68/Sr D1 Rabbit Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00602-1)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Clonality
Monoclonal
Clone Number
GBE-3
Isotype
Rabbit IgG
Immunogen
A synthesized peptide derived from human CD68
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M00602-1 is reactive to CD68 in Human, Mouse, Rat
Reconstitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Observed Molecular Weight
32-42 kDa, 65 kDa, 75 kDa
Calculated molecular weight
37408 MW
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M00602-1 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:1000
Validation Images & Assay Conditions
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All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
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Western blot analysis of CD68 expression in Jurkat cell lysate.
Protein Target Info & Infographic
Gene/Protein Information For CD68 (Source: Uniprot.org, NCBI)
Gene Name
CD68
Full Name
Macrosialin
Weight
37408 MW
Superfamily
LAMP family
Alternative Names
Macrosialin;Gp110;CD68;CD68; CD68 GP110, LAMP4, SCARD1 CD68 molecule macrosialin|CD68 |macrophage CD68|scavenger receptor class D, member 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CD68, check out the CD68 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CD68: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CD68/Sr D1 Rabbit Monoclonal Antibody (M00602-1)
Hello CJ!
M00602-1 has been cited in 18 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Fan Guo,Wei na Kong,Gang Zhao et al.The Correlation Between Tumor-associated Macrophage Infiltration and Progression in Cervical Carcinoma, 01 December 2020, PREPRINT (Version 1) available at Research Square[+https://doi.org/10.21203/rs.3.rs-115339/v1+]
Species: Human
M00602-1 usage in article: APP:IHC, SAMPLE:CERVICAL TISSUE, DILUTION:1:50
Macrophage-stimulated microRNA expression in mural cells promotes transplantation-induced neointima formation
Inhibition of poly (ADP-ribose) polymerase-1 protects chronic alcoholic liver injury
UPLC/Q-TOFMS-Based Metabolomics Approach to Reveal the Protective Role of Other Herbs in An-Gong-Niu-Huang Wan Against the Hepatorenal Toxicity of %u2026
Targeting Src attenuates peritoneal fibrosis and inhibits the epithelial to mesenchymal transition
Expressions Profiles of the Proteins Associated with Carbohydrate Metabolism in Rat Liver Regeneration
Blockage of Galectin-receptor Interactions by ?-lactose Exacerbates Plasmodium berghei-induced Pulmonary Immunopathology
Inhibition of EGF Receptor Blocks the Development and Progression of Peritoneal Fibrosis.
CD40 Generation 2.5 Antisense Oligonucleotide Treatment Attenuates Doxorubicin-induced Nephropathy and Kidney Inflammation
1,25(OH)2D3 downregulates the Toll-like receptor 4-mediated inflammatory pathway and ameliorates liver injury in diabetic rats
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Customer Q&As
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4 Customer Q&As for Anti-CD68/Sr D1 Rabbit Monoclonal Antibody
Question
We have seen staining in rat skin. Any tips? Is anti-CD68/Sr D1 Rabbit Monoclonal antibody supposed to stain skin positively?
Verified Customer
Verified customer
Asked: 2019-09-03
Answer
From literature skin does express CD68. From Uniprot.org, CD68 is expressed in leukocyte, spleen umbilical cord blood, adipose tissue, skin, platelet, liver, among other tissues. Regarding which tissues have CD68 expression, here are a few articles citing expression in various tissues:
Adipose tissue, Pubmed ID: 16625196
Liver, Pubmed ID: 19159218
Platelet, Pubmed ID: 16263699
Skin, Pubmed ID: 15489334
Spleen, and Umbilical cord blood, Pubmed ID: 14702039
Boster Scientific Support
Answered: 2019-09-03
Question
We are currently using anti-CD68/Sr D1 Rabbit Monoclonal antibody M00602-1 for human tissue, and we are content with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it true that the antibody can work on primate tissues as well?
Verified Customer
Verified customer
Asked: 2019-06-14
Answer
The anti-CD68/Sr D1 Rabbit Monoclonal antibody (M00602-1) has not been tested for cross reactivity specifically with primate tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in primate you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2019-06-14
Question
I am interested in using your anti-CD68/Sr D1 Rabbit Monoclonal antibody for negative regulation of dendritic cell antigen processing and presentation studies. Has this antibody been tested with western blotting on jurkat cell lysate? We would like to see some validation images before ordering.
Verified Customer
Verified customer
Asked: 2017-09-04
Answer
We appreciate your inquiry. This M00602-1 anti-CD68/Sr D1 Rabbit Monoclonal antibody is tested on jurkat cell lysate. It is guaranteed to work for WB in human, mouse, rat. Our Boster guarantee will cover your intended experiment even if the sample type has not been be directly tested.
Boster Scientific Support
Answered: 2017-09-04
Question
My team were content with the WB result of your anti-CD68/Sr D1 Rabbit Monoclonal antibody. However we have seen positive staining in leukocyte isoform short: cell membrane using this antibody. Is that expected? Could you tell me where is CD68 supposed to be expressed?
B. Wu
Verified customer
Asked: 2017-07-11
Answer
Based on literature, leukocyte does express CD68. Generally CD68 expresses in isoform short: cell membrane. Regarding which tissues have CD68 expression, here are a few articles citing expression in various tissues:
Adipose tissue, Pubmed ID: 16625196
Liver, Pubmed ID: 19159218
Platelet, Pubmed ID: 16263699
Skin, Pubmed ID: 15489334
Spleen, and Umbilical cord blood, Pubmed ID: 14702039
Boster Scientific Support
Answered: 2017-07-11
