Anti-CD153/TNFSF8 Antibody

CD30 Ligand/TNFSF8 antibody

Boster Bio Anti-CD153/TNFSF8 Antibody catalog # RP1103. Tested in Flow Cytometry, IHC applications. This antibody reacts with Human. Cited in 1 publication(s).

Product Info Summary

SKU: RP1103
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: Flow Cytometry, IHC

Product Name

Anti-CD153/TNFSF8 Antibody

View all CD30 Ligand/TNFSF8 Antibodies

SKU/Catalog Number

RP1103

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-CD153/TNFSF8 Antibody catalog # RP1103. Tested in Flow Cytometry, IHC applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-CD153/TNFSF8 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # RP1103)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human CD153 recombinant protein (Position: Q63-D234). Human CD153 shares 75% amino acid (aa) sequence identity with mouse CD153.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

RP1103 is reactive to TNFSF8 in Human

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

86 kDa

Calculated molecular weight

26017 MW

Background of CD30 Ligand/TNFSF8

CD153 is a ligand for CD30. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

RP1103 is guaranteed for Flow Cytometry, IHC Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, By Heat
Flow Cytometry, 1-3μg/1x106cells

Positive Control

IHC: human tonsil tissue
FCM: U937 cell

Validation Images & Assay Conditions

Gene/Protein Information For TNFSF8 (Source: Uniprot.org, NCBI)

Gene Name

TNFSF8

Full Name

Tumor necrosis factor ligand superfamily member 8

Weight

26017 MW

Superfamily

tumor necrosis factor family

Alternative Names

Tumor necrosis factor ligand superfamily member 8;CD30 ligand;CD30-L;CD153;TNFSF8;CD30L, CD30LG; TNFSF8 CD153, CD30L, CD30LG, TNLG3A TNF superfamily member 8 tumor necrosis factor ligand superfamily member 8|CD153 |CD30 ligand|CD30 ligand|CD30-L|tumor necrosis factor (ligand) superfamily, member 8|tumor necrosis factor ligand 3A|tumor necrosis factor superfamily member 8

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on TNFSF8, check out the TNFSF8 Infographic

TNFSF8 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for TNFSF8: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

RP1103 has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

CD30 Is Highly Expressed in Chronic Obstructive Pulmonary Disease and Induces the Pulmonary Vascular Remodeling

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1 Customer Q&As for Anti-CD153/TNFSF8 Antibody

Question

We are currently using anti-CD153/TNFSF8 antibody RP1103 for human tissue, and we are content with the IHC results. The species of reactivity given in the datasheet says human. Is it true that the antibody can work on feline tissues as well?

Verified Customer

Verified customer

Asked: 2020-04-06

Answer

The anti-CD153/TNFSF8 antibody (RP1103) has not been validated for cross reactivity specifically with feline tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in feline you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2020-04-06

Order DetailsPrice
RP1103

100μg

$370
RP1103-10ug

10μg sample (liquid)

$99
RP1103-Biotin

100 μg Biotin conjugated

$570
RP1103-Cy3

100 μg Cy3 conjugated

$570
RP1103-Dylight488

100 μg Dylight488 conjugated

$570
RP1103-Dylight550

100 μg Dylight550 conjugated

$570
RP1103-Dylight594

100 μg Dylight594 conjugated

$570
RP1103-FITC

100 μg FITC conjugated

$570
RP1103-HRP

100 μg HRP conjugated

$570
RP1103-APC

100 μg APC conjugated

$670
RP1103-PE

100 μg PE conjugated

$670
RP1103-iFluor647

100 μg iFluor647 conjugated

$670
RP1103-carrier-free

Carrier Free

$370

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Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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