Product Info Summary
SKU: | A00390 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human |
Host: | Rabbit |
Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-C-C chemokine receptor type 7 CCR7 Antibody
SKU/Catalog Number
A00390
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-C-C chemokine receptor type 7 CCR7 Antibody (Catalog # A00390). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.
Storage & Handling
CCR7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-C-C chemokine receptor type 7 CCR7 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00390)
Host
Rabbit
Contents
CCR7 antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
CCR7 antibody was raised against a 15 amino acid peptide near the center of human CCR7. The immunogen is located within amino acids 180 - 230 of CCR7.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
CCR7 antibody is human specific. CCR7 antibody is predicted to not cross-react with other CCR proteins.
Reactive Species
A00390 is reactive to CCR7 in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
42874 MW
Background of CCR7
The CCR7 protein is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation (1,2). The chemokine (C-C motif) ligand 19 (CCL19) has been reported to be a specific ligand of this receptor (3).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A00390 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
CCR7 antibody can be used for detection of CCR7 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of CCR7 in human spleen tissue lysate with CCR7 antibody at 1 μg/ml.
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Immunohistochemistry of CCR7 in human spleen tissue with CCR7 antibody at 5 μg/mL.
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Immunofluorescence of CCR7 in human spleen tissue with CCR7 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For CCR7 (Source: Uniprot.org, NCBI)
Gene Name
CCR7
Full Name
C-C chemokine receptor type 7
Weight
42874 MW
Superfamily
G-protein coupled receptor 1 family
Alternative Names
BLR2, EBI1, CD197, CDw197, CMKBR7, EVI1, C-C chemokine receptor type 7, BLR2, C-C CKR-7 CCR7 BLR2, CC-CKR-7, CCR-7, CD197, CDw197, CMKBR7, EBI1 C-C motif chemokine receptor 7 C-C chemokine receptor type 7|Bukitts lymphoma receptor 2|CC chemokine receptor 7|EBV-induced G protein-coupled receptor 1|Epstein-Barr virus induced gene 1|Epstein-Barr virus-induced G-protein coupled receptor 1|MIP-3 beta receptor|chemokine (C-C motif) receptor 7|lymphocyte-specific G protein-coupled peptide receptor
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CCR7, check out the CCR7 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CCR7: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-C-C chemokine receptor type 7 CCR7 Antibody (A00390)
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