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- Table of Contents
1 Citations 6 Q&As
Facts about C-C chemokine receptor type 7.
Receptor for the MIP-3-beta chemokine.
Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions..
Human | |
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Gene Name: | CCR7 |
Uniprot: | P32248 |
Entrez: | 1236 |
Belongs to: |
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G-protein coupled receptor 1 family |
BLR2; BLR2C-C chemokine receptor type 7; C-C CKR-7; CC-CKR-7; CCR7; CCR-7; CD197 antigen; CD197; CDw197; CDw197CC chemokine receptor 7; chemokine (C-C motif) receptor 7; CMKBR7; CMKBR7chemokine (C-C) receptor 7; EBI1; EBI1EBV-induced G protein-coupled receptor 1; EBV-induced G-protein coupled receptor 1; Epstein-Barr virus induced gene 1; Epstein-Barr virus induced G-protein coupled receptor; Epstein-Barr virus-induced G-protein coupled receptor 1; EVI1; lymphocyte-specific G protein-coupled peptide receptor; MIP-3 beta receptor
Mass (kDA):
42.874 kDA
Human | |
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Location: | 17q21.2 |
Sequence: | 17; NC_000017.11 (40553769..40565472, complement) |
Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7.
Cell membrane; Multi-pass membrane protein.
PMID: 8383238 by Birkenbach M.P., et al. Epstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptors.
PMID: 7851893 by Schweickart V.L., et al. Cloning of human and mouse EBI1, a lymphoid-specific G-protein- coupled receptor encoded on human chromosome 17q12-q21.2.
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