Anti-Bov CD62L Purified SELL Monoclonal Antibody

Product Name

Anti-Bov CD62L Purified SELL Monoclonal Antibody

View all L-Selectin/CD62L Antibodies

SKU/Catalog Number

M00652

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Bov CD62L Purified SELL Monoclonal Antibody (Catalog# M00652). Tested in Flow Cytometry, IP, ICC application(s). This antibody reacts with Cow, Human.

Storage & Handling

Store at 2-8°C. Do not freeze.

Cite This Product

Anti-Bov CD62L Purified SELL Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00652)

Host

Mouse

Contents

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Clonality

Monoclonal

Clone Number

IVA94

Isotype

Mouse IgG1

Immunogen

Bovine leukocytes. The antibody IVA94 reacts with an extracellular epitope of CD62L antigen (bovine). CD62L (L-selectin) is a 74-95 kDa single chain type I glycoprotein expressed on most peripheral blood B lymphocytes, T lymphocytes, monocytes and granulocytes; it is also present on a subset of NK cells and certain hematopoietic malignant cells.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M00652 is reactive to SELL in Cow, Human

Reconstitution

Observed Molecular Weight

42 kDa

Calculated molecular weight

84871 MW

Background of L-Selectin/CD62L

CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

M00652 is guaranteed for Flow Cytometry, IP, ICC Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Flow cytometry: 1-4 μg/ml.

Validation Images & Assay Conditions

Gene/Protein Information For SELL (Source: Uniprot.org, NCBI)

Alternative Names

L-selectin, LSEL, SELL, LAM1, LECAM1, LEU8, LNHR, LYAM1, PLNHR SELL CD62L, LAM1, LECAM1, LEU8, LNHR, LSEL, LYAM1, PLNHR, TQ1 selectin L L-selectin|CD62 -like family member L|gp90-MEL|leukocyte surface Leu-8|leukocyte-endothelial cell adhesion molecule 1|lymph node homing receptor|lymphocyte adhesion molecule 1|pln homing receptor

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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