Data

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Key=store_id
Key=entity_id, value=53730
Key=attribute_set_id, value=4
Key=type_id, value=simple
Key=sku, value=EKC1294
Key=has_options, value=0
Key=required_options, value=0
Key=created_at, value=2019-02-12 00:20:57
Key=updated_at, value=2024-09-26 01:01:21
Key=mst_search_weight, value=0
Key=status, value=Enabled
Key=name, value=IKK-beta Colorimetric Cell-Based ELISA Kit
Key=cj_search_index
Key=publication_count, value=0
Key=qty_in_warehouses
Key=is_recurring, value=No
Key=visibility, value=Catalog, Search
Key=tax_class_id, value=Taxable Goods
Key=featured, value=No
Key=featured_image, value=Yes
Key=fb_product, value=
Key=custom_product_page, value=No
Key=free_shipping, value=No
Key=template, value=cell-based-elisa-kits
Key=price, value=480.0000
Key=weight, value=1.0000
Key=meta_title, value=IKK-beta Colorimetric Cell-Based ELISA Kit Price | BosterBio
Key=meta_description, value=IKK-beta Colorimetric Cell-Based ELISA Kit EKC1294
Key=image, value=/b/o/boster-box.png
Key=small_image, value=/b/o/boster-box.png
Key=thumbnail, value=/b/o/boster-box.png
Key=url_key, value=ikk-beta-colorimetric-cell-based-elisa-kit-ekc1294-boster
Key=url_path, value=ikk-beta-colorimetric-cell-based-elisa-kit-ekc1294-boster
Key=options_container, value=Product Info Column
Key=image_label, value=Boster Kit Box
Key=small_image_label, value=Boster Kit Box
Key=thumbnail_label, value=Boster Kit Box
Key=msrp_display_actual_price_type, value=
Key=gift_message_available, value=No
Key=size, value=1 kit, containing one 96-well plate and all necessary reagents
Key=gene_full_name, value=Inhibitor of nuclear factor kappa-B kinase subunit beta
Key=uniprot_id, value=O14920
Key=assay_range, value=> 5000 cells/well
Key=applications, value=ELISA
Key=reactivity, value=Human, Mouse, Rat
Key=source_company, value=AssayBiotech CB5359; Cost: 240
Key=molecular_weight, value=86564 MW
Key=product_category, value=Cell-Based ELISA Kits
Key=rating_value, value=100
Key=review_count, value=6
Key=mp_exclude_sitemap, value=No
Key=cj_related_products, value=Immunology:PA2223|EK1421|M00360^Innate Immunity:A00144-Dyl550^mTOR Pathway:PA2036-1^Sensitization:A06347
Key=description, value=The IKK-beta Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor IKK-beta protein expression profile in cells. The kit can be used for measuring the relative amounts of IKK-beta in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on IKK-beta.
Key=short_description, value=The IKK-beta Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor IKK-beta protein expression profile in cells. The kit can be used for measuring the relative amounts of IKK-beta in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on IKK-beta.
Key=gene_name, value=IKBKB
Key=synonyms, value=I-kappa-B kinase 2;I-kappa-B-kinase beta;IKK-B;IKK-beta;IKK2;IKKB;IkBKB;NFKBIKB;Nuclear factor NF-kappa-B inhibitor kinase beta;kinase IKK-beta
Key=sample_type, value=Cell lines
Key=kit_components, value=IKK-beta
Key=subcellular_localization, value=Cytoplasm. Nucleus. Membrane raft. Colocalized with DPP4 in membrane rafts.
Key=tissue_specificity, value=Highly expressed in heart, placenta, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis and peripheral blood.
Key=protein_function, value= Serine kinase that plays an essential role in the NF- kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis. In addition to the NF-kappa-B inhibitors, phosphorylates several other components of the signaling pathway including NEMO/IKBKG, NF-kappa-B subunits RELA and NFKB1, as well as IKK-related kinases TBK1 and IKBKE. IKK-related kinase phosphorylations may prevent the overproduction of inflammatory mediators since they exert a negative regulation on canonical IKKs. Phosphorylates FOXO3, mediating the TNF- dependent inactivation of this pro-apoptotic transcription factor. Also phosphorylates other substrates including NCOA3, BCL10 and IRS1. Within the nucleus, acts as an adapter protein for NFKBIA degradation in UV-induced NF-kappa-B activation.
Key=storage, value=Store at 4°C for up to 6 months.
Key=custom_attribute_1, value=IKK-beta
Key=options
Key=media_gallery
Key=extension_attributes
Key=tier_price
Key=tier_price_changed
Key=category_ids
Key=quantity_and_stock_status
Key=is_salable
Key=website_ids
Key=request_path
Key=rating_summary
Key=_cache_instance_store_filter
Key=media_gallery_images