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Product Info Summary
| SKU: | A04007 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-ZIP8 SLC39A8 Antibody
View all SLC39A8/ZIP8 Antibodies
SKU/Catalog Number
A04007
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-ZIP8 SLC39A8 Antibody (Catalog # A04007). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.
Storage & Handling
ZIP8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-ZIP8 SLC39A8 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04007)
Host
Rabbit
Contents
ZIP8 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
ZIP8 antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of human ZIP8. The immunogen is located within the last 50 amino acids of ZIP8.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
ZIP8 antibody is predicted to not cross-react with other ZIP family members.
Reactive Species
A04007 is reactive to SLC39A8 in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
49631 MW
Background of SLC39A8/ZIP8
The zinc transporter ZIP8, also known as SLC39A9, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP8 is glycosylated and located at the plasma membrane and mitochondria. It has been identified as the transporter responsible for transport of the toxic Cadmium cation. ZIP8 has also been suggested to play a role in the regulation of interferon-gamma expression in activated human T cells.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A04007 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ZIP8 antibody can be used for detection of ZIP8 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of ZIP8 in human spleen tissue lysate with ZIP8 antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of ZIP8 in human spleen tissue with ZIP8 antibody at 5 μg/mL.
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Immunofluorescence of ZIP8 in human spleen tissue with ZIP8 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For SLC39A8 (Source: Uniprot.org, NCBI)
Gene Name
SLC39A8
Full Name
Zinc transporter ZIP8
Weight
49631 MW
Superfamily
ZIP transporter (TC 2.A.5) family
Alternative Names
ZIP8, PP3105, BIGM103, LZT-Hs6, ZIP8, Zinc transporter ZIP8, BCG-induced integral membrane protein in monocyte clone 103 protein SLC39A8 BIGM103, CDG2N, LZT-Hs6, PP3105, ZIP8 solute carrier family 39 member 8 metal cation symporter ZIP8|BCG induced integral membrane protein BIGM103|BCG-induced integral membrane protein in monocyte clone 103 protein|LIV-1 subfamily of ZIP zinc transporter 6|ZIP-8|Zrt- and Irt-like protein 8|solute carrier family 39 (metal ion transporter), member 8|zinc transporter ZIP8
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SLC39A8, check out the SLC39A8 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SLC39A8: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ZIP8 SLC39A8 Antibody (A04007)
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