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Product Info Summary
| SKU: | A04761 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-ZIP14 SLC39A14 Antibody
SKU/Catalog Number
A04761
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-ZIP14 SLC39A14 Antibody (Catalog # A04761). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
ZIP14 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-ZIP14 SLC39A14 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04761)
Host
Rabbit
Contents
ZIP14 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
ZIP14 antibody was raised against a 16 amino acid synthetic peptide near the center of human ZIP14. The immunogen is located within amino acids 230 - 280 of ZIP14.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least three isoforms of ZIP14 are known to exist; this antibody will detect both isoforms. ZIP14 antibody is predicted to not cross-react with other ZIP family members.
Reactive Species
A04761 is reactive to SLC39A14 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
54212 MW
Background of SLC39A14
The zinc transporter ZIP14, also known as SLC39A14, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP14 is a glycosylated multipass plasma membrane protein that belongs to the ZIP transporter subfamily LIV-1. ZIP14 has been shown to contribute to the hypozincemia of inflammation and infection and is regulated in the liver by IL-6. In addition to zinc, ZIP14 is also involved in the cellular uptake of non-transferrin-bound iron as well as iron bound to transferrin.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A04761 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ZIP14 antibody can be used for detection of ZIP14 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of ZIP14 in human spleen tissue lysate with ZIP14 antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of ZIP14 in mouse liver tissue with ZIP14 antibody at 2.5 μg/mL.
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Immunofluorescence of ZIP14 in Mouse Liver tissue with ZIP14 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For SLC39A14 (Source: Uniprot.org, NCBI)
Gene Name
SLC39A14
Full Name
Zinc transporter ZIP14
Weight
54212 MW
Superfamily
ZIP transporter (TC 2.A.5) family
Alternative Names
NET34, ZIP14, cig19, LZT-Hs4, KIAA0062, Zinc transporter ZIP14, LIV-1 subfamily of ZIP zinc transporter 4 SLC39A14 HCIN, HMNDYT2, LZT-Hs4, NET34, ZIP14, cig19 solute carrier family 39 member 14 metal cation symporter ZIP14|LIV-1 subfamily of ZIP zinc transporter 4|Zinc transporter ZIP14|Zrt-, Irt-like protein 14|solute carrier family 39 (metal ion transporter), member 14|solute carrier family 39 (zinc transporter), member 14|zrt- and Irt-like protein 14
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SLC39A14, check out the SLC39A14 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SLC39A14: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ZIP14 SLC39A14 Antibody (A04761)
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