Anti-XRCC1 Antibody Picoband® (monoclonal, 10E10)

XRCC1 antibody

Boster Bio Anti-XRCC1 Antibody Picoband® (monoclonal, 10E10) catalog # M00571-2. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Info Summary

SKU: M00571-2
Size: 100 μg/vial
Reactive Species: Human
Host: Mouse
Application: Flow Cytometry, IF, ICC, WB

Product Name

Anti-XRCC1 Antibody Picoband® (monoclonal, 10E10)

View all XRCC1 Antibodies

SKU/Catalog Number

M00571-2

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-XRCC1 Antibody Picoband® (monoclonal, 10E10) catalog # M00571-2. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Cite This Product

Anti-XRCC1 Antibody Picoband® (monoclonal, 10E10) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00571-2)

Host

Mouse

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Clonality

Monoclonal

Clone Number

10E10

Isotype

IgG2b

Immunogen

E. coli-derived human XRCC1 recombinant protein (Position: E538-A633).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

M00571-2 is reactive to XRCC1 in Human

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 µg/ml.

Observed Molecular Weight

95 kDa

Calculated molecular weight

69.477kDa

Background of XRCC1

XRCC1(X-RAY REPAIR, COMPLEMENTING DEFECTIVE, IN CHINESE HAMSTER, 1) is a DNA repair protein which complexes with DNA ligase III. The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. The XRCC1 gene is mapped to 19q13.31. The XRCC1 interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. XRCC1 is phosphorylated in vivo and in vitro by CK2, and CK2 phosphorylation of XRCC1 on ser518, thr519, and thr523 largely determines aprataxin binding to XRCC1 through its FHA domain.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

M00571-2 is guaranteed for Flow Cytometry, IF, ICC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.25-0.5 µg/ml, Human
Immunocytochemistry/Immunofluorescence, 5 µg/ml, Human
Flow Cytometry (Fixed), 1-3 µg/1x106 cells, Human

Positive Control

WB: human Hela whole cell, human 293T whole cell, human K562 whole cell, human Jurkat whole cell, human HEL whole cell, human A431 whole cell
ICC/IF: A431 cell
FCM: Hela cell

Validation Images & Assay Conditions

Gene/Protein Information For XRCC1 (Source: Uniprot.org, NCBI)

Gene Name

XRCC1

Full Name

DNA repair protein XRCC1

Weight

69.477kDa

Alternative Names

Glutathione S-transferase Mu 1; GST HB subunit 4; GST class-mu 1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GTH4; GSTM1; GST1 XRCC1 RCC, SCAR26 X-ray repair cross complementing 1 DNA repair protein XRCC1|X-ray repair complementing defective repair in Chinese hamster cells 1|X-ray repair cross-complementing protein 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on XRCC1, check out the XRCC1 Infographic

XRCC1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for XRCC1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
M00571-2

100μg

$370
M00571-2-10ug

10μg sample (liquid)

$99
M00571-2-Biotin

100 μg Biotin conjugated

$570
M00571-2-Cy3

100 μg Cy3 conjugated

$570
M00571-2-Dylight488

100 μg Dylight488 conjugated

$570
M00571-2-Dylight550

100 μg Dylight550 conjugated

$570
M00571-2-Dylight594

100 μg Dylight594 conjugated

$570
M00571-2-FITC

100 μg FITC conjugated

$570
M00571-2-HRP

100 μg HRP conjugated

$570
M00571-2-APC

100 μg APC conjugated

$670
M00571-2-PE

100 μg PE conjugated

$670
M00571-2-iFluor647

100 μg iFluor647 conjugated

$670
M00571-2-carrier-free

Carrier Free

$370

More conjugates/formats

Free Secondary Antibody

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M00571-2
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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