Anti-VE-Cadherin CDH5-Monoclonal Antibody

Product Name

Anti-VE-Cadherin CDH5-Monoclonal Antibody

View all VE-Cadherin Antibodies

SKU/Catalog Number

M02632-3

Size

100ul

Form

Liquid

Description

Boster Bio Anti-VE-Cadherin CDH5-Monoclonal Antibody catalog # M02632-3. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-VE-Cadherin CDH5-Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M02632-3)

Host

Mouse

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Monoclonal

Clone Number

800000

Isotype

IgG

Immunogen

synthetic peptide derived from VE-Cadherin.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

M02632-3 is reactive to CDH5 in Human, Mouse, Rat

Applications

M02632-3 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

87528 MW

Background of VE-Cadherin

Anti-Procalcitonin antibody detects human Procalcitonin. Procalcitonin is a peptide hormone mainly produced by the C cells of the thyroid and certain endocrine cells of the lung. Under normal expression conditions, procalcitonin is immediately cleaved into three specific fragments, a N terminal residue, calcitonin and katacalcin. Levels of unprocessed procalcitonin rise significantly after bacterial infection, trauma or shock. This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-2000
ELISA 1:10000-20000

Validation Images & Assay Conditions

Click image to see more details

Figure 1. Immunohistochemistry validation of CDH5 using Anti-VE-Cadherin CDH5 Monoclonal Antibody (M02632-3).

Immunohistochemical analysis of paraffin-embedded Rat Heart Tissue using VE-Cadherin Mouse mAb diluted at 1:200.
For more protocol information of IHC

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Figure 2. Immunohistochemistry validation of CDH5 using Anti-VE-Cadherin CDH5 Monoclonal Antibody (M02632-3).

Immunohistochemical analysis of paraffin-embedded Human Heart Tissue using VE-Cadherin Mouse mAb diluted at 1:200.
For more protocol information of IHC

Gene/Protein Information For CDH5 (Source: Uniprot.org, NCBI)

Alternative Names

7B4 antigen; 7B4; cadherin 5, type 2 (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular epithelium); Cadherin-5; CD144 antigen; CD144; CDH5; endothelial-specific cadherin; FLJ17376; Vascular endothelial cadherin; VECadherin; VE-Cadherin CDH5 7B4, CD144 cadherin 5 cadherin-5|7B4 antigen|VE-cadherin|cadherin 5, type 2 (vascular endothelium)|cadherin 5, type 2, VE-cadherin (vascular epithelium)|cd144 antigen|endothelial-specific cadherin|vascular endothelial cadherin

For more info on CDH5, check out the CDH5 Infographic

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In this infographic, you will see the following information for CDH5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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