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Product Info Summary
| SKU: | A04275 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, IF, ICC, WB |
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Product info
Product Name
Anti-TRIP6 Antibody
SKU/Catalog Number
A04275
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-TRIP6 Antibody (Catalog # A04275). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse.
Storage & Handling
TRIP6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-TRIP6 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04275)
Host
Rabbit
Contents
TRIP6 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
TRIP6 antibody was raised against a 15 amino acid synthetic peptide near the center of human TRIP6. The immunogen is located within amino acids 190 - 240 of TRIP6.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
ERAP2 antibody is human reactive. Multiple isoforms of ERAP2 are known to exist. ERAP2 antibody is predicted to not cross-react with ERAP1.
Reactive Species
A04275 is reactive to TRIP6 in Human, Mouse
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
50288 MW
Background of TRIP6
TRIP6 (Thyroid receptor interacting protein 6) is a zyxin-related focal adhesion molecule involved in cell motility and antiapoptotic responses. TRIP6 is predominantly expressed in kidney, liver and lung. It has three LIM domains, a PDZ-binding motif, a Crk SH2-binding motif and/or other protein interacting domains. TRIP6 regulates NF-κB activation and interacts with RICK and TRAF2, proteins that are involved in TNF signaling. TRIP6 antagonizes Fas-induced apoptosis and promotes Fas-mediated cell migration in apoptosis-resistant glioma cells via Src-dependent phosphorylation of TRIP6 at Tyr-55.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A04275 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TRIP6 antibody can be used for detection of TRIP6 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of TRIP6 in A431 cell lysate with TRIP6 antibody at 1 μg/mL.
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Immunocytochemistry of TRIP6 in HeLa cells with TRIP6 antibody at 10 μg/mL.
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Immunofluorescence of TRIP6 in HeLa cells with TRIP6 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For TRIP6 (Source: Uniprot.org, NCBI)
Gene Name
TRIP6
Full Name
Thyroid receptor-interacting protein 6
Weight
50288 MW
Superfamily
zyxin/ajuba family
Alternative Names
OIP1, OIP-1, ZRP-1, TRIP-6, TRIP6i2, OIP1, Thyroid receptor-interacting protein 6, Opa-interacting protein 1, TR-interacting protein 6 TRIP6 OIP-1, OIP1, TRIP-6i2, ZRP-1, TRIP6 thyroid hormone receptor interactor 6 thyroid receptor-interacting protein 6|OPA-interacting protein 1|TR-interacting protein 6|thyroid hormone receptor interacting protein 6|zyxin related protein 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TRIP6, check out the TRIP6 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TRIP6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TRIP6 Antibody (A04275)
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