TRIP6 Antibodies

AND TRIP6 ELISA kits, TRIP6 Proteins

Many biological assays use antibodies to detect TRIP6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRIP6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRIP6 antibodies...

We validate the specificity of these antibodies to TRIP6 by testing them on tissues known to express TRIP6 positively and negatively. Browse below to find the TRIP6 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRIP6 Infographic by Boster Bio

All TRIP6 Products

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Product

Figures

Specificity

Applications

Price

Anti-TRIP6 Antibody

Human, Mouse

ELISA, IF, ICC, WB

$449
Cat # A04275
0.1 mg

TRIP6 (NM_003302) Human Over-expression Lysate

Human

$628
Cat # LS007205
100 µg

TRIP6 Overview

Facts about Thyroid receptor-interacting protein 6.

TRIP6 3D structure. Source: alphafold

Thyroid receptor-interacting protein 6 (TRIP6)

Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphatidic acid-induced cell adhesion and migration.

Acts as a transcriptional coactivator for NF-kappa-B and JUN, and mediates the transrepression of these transcription factors induced by glucocorticoid receptor. .

Gene Information

Human
Gene Name:	TRIP6
Uniprot:	Q15654
Entrez:	7205

Family

Belongs to:

zyxin/ajuba family

Alternative Names

MGC10556; MGC10558; MGC29959; MGC3837; MGC4423; OIP1OIP-1; Opa-interacting protein 1; thyroid hormone receptor interactor 6; thyroid receptor-interacting protein 6; TR-interacting protein 6; ZRP-1TRIP-6; zyxin related protein 1; Zyxin-related protein 1

Molecular Weight

Mass (kDA):
50.288 kDA

Genomic Context


Human

Location:	7q22.1
Sequence:	7; NC_000007.14 (100867387..100873454)

Tissue Specificity

Abundantly expressed in kidney, liver and lung. Lower levels in heart, placenta and pancreas. Expressed in colonic epithelial cells. Up-regulated in colonic tumors.

Subcellular Localizations

Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Nucleus. Cytoplasm. Shuttles between nucleus and cytoplasm (PubMed:16624523). Colocalizes with actin (PubMed:10826496).

Diseases

Tissue Adhesions
Malignant Neoplasms
Neoplasms
Cell Invasion
Lipoma
Cell Transformation, Neoplastic
Malignant Paraganglionic Neoplasm
Salmonella Infections
Neoplasm Metastasis
Glioma
Neoplasm Invasiveness
Carcinoma

Nervousness
Dental Plaque
Malignant Neoplasm Of Ovary
Mammary Neoplasms
Ovarian Neoplasm
Uterine Fibroids

Pathways

Cell Adhesion
Cell Migration
Cell Motility
Nuclear Export
Localization
Transport
Cell Proliferation
Regulation Of Cell Adhesion
Pathogenesis
Rna Interference
Osteoclast Fusion
System Development
Cell Cycle

Wound Healing
Focal Adhesion Assembly
Cell-cell Adhesion
Oncogenesis
Mitosis
Dna Methylation
Methylation

PTMs

Phosphorylation
Methylation

Dephosphorylation
Ribosylation

Research Areas

Core ESC-Like Genes
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRIP6

References

PMID: 9598321 by Yi J., et al. The human TRIP6 gene encodes a LIM domain protein and maps to chromosome 7q22, a region associated with tumorigenesis.

PMID: 10400701 by Murthy K.K., et al. ZRP-1, a zyxin-related protein, interacts with the second PDZ domain of the cytosolic protein tyrosine phosphatase hPTP1E.