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Key=description, value=Boster Bio Anti-SEK1/MKK4 (Ab-261) MAP2K4 Antibody (Catalog # A01725). Tested in IHC, IF applications. This antibody reacts with Human, Mouse, Rat.
Key=short_description, value=Boster Bio Anti-SEK1/MKK4 (Ab-261) MAP2K4 Antibody (Catalog # A01725). Tested in IHC, IF applications. This antibody reacts with Human, Mouse, Rat.
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Key=contents, value=Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Key=background, value=Dual specificity kinase that activates the JUN kinases MAPK8 (JNK1) and MAPK9 (JNK2) as well as MAPK14 (p38) but not MAPK1 (ERK2) or MAPK3 (ERK1).

Wang W, et al. (2002) Mol Cell Biol; 22(10): 3389-403.
Leung IW, et al. (2001)J Biol Chem; 276(3): 1961-7.
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Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:200
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Key=immunogen, value=Peptide sequence around aa.259~263 (A-K-T-R-D) derived from Human SEK1/MKK4.
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Anti-SEK1/MKK4 (Ab-261) MAP2K4 Antibody

MKK4/MEK4 antibody

Boster Bio Anti-SEK1/MKK4 (Ab-261) MAP2K4 Antibody (Catalog # A01725). Tested in IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A01725
Size: 100 µl
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IF, IHC

Product Name

Anti-SEK1/MKK4 (Ab-261) MAP2K4 Antibody

View all MKK4/MEK4 Antibodies

SKU/Catalog Number

A01725

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-SEK1/MKK4 (Ab-261) MAP2K4 Antibody (Catalog # A01725). Tested in IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-SEK1/MKK4 (Ab-261) MAP2K4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01725)

Host

Rabbit

Contents

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Peptide sequence around aa.259~263 (A-K-T-R-D) derived from Human SEK1/MKK4.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A01725 is reactive to MAP2K4 in Human, Mouse, Rat

Reconstitution

Observed Molecular Weight

39 kDa

Calculated molecular weight

18848 MW

Background of MKK4/MEK4

Dual specificity kinase that activates the JUN kinases MAPK8 (JNK1) and MAPK9 (JNK2) as well as MAPK14 (p38) but not MAPK1 (ERK2) or MAPK3 (ERK1).

Wang W, et al. (2002) Mol Cell Biol; 22(10): 3389-403.
Leung IW, et al. (2001)J Biol Chem; 276(3): 1961-7.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Applications

A01725 is guaranteed for IF, IHC Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Predicted MW: 44kd
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:200

Validation Images & Assay Conditions

Gene/Protein Information For MAP2K4 (Source: Uniprot.org, NCBI)

Gene Name

MAP2K4

Full Name

Dual specificity mitogen-activated protein kinase kinase 4

Weight

18848 MW

Superfamily

protein kinase superfamily

Alternative Names

CD99 antigen;12E7;E2 antigen;Protein MIC2;T-cell surface glycoprotein E2;CD99;CD99;MIC2, MIC2X, MIC2Y; MAP2K4 JNKK, JNKK1, MAPKK4, MEK4, MKK4, PRKMK4, SAPKK-1, SAPKK1, SEK1, SERK1, SKK1 mitogen-activated protein kinase kinase 4 dual specificity mitogen-activated protein kinase kinase 4|JNK-activated kinase 1|JNK-activating kinase 1|MAP kinase kinase 4|MAPK/ERK kinase 4|MAPKK 4|MEK 4|SAPK/ERK kinase 1|c-Jun N-terminal kinase kinase 1|stress-activated protein kinase kinase 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on MAP2K4, check out the MAP2K4 Infographic

MAP2K4 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for MAP2K4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A01725

100ul

$360

Free Secondary Antibody

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A01725
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$360.00

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