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Key=sku, value=A00818-2
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Key=created_at, value=2021-12-01 02:59:53
Key=updated_at, value=2024-10-25 05:03:54
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Key=status, value=Enabled
Key=name, value=Anti-RIP2/RIPK2 Antibody Picoband®
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Key=badge, value=free-antibody-validation
Key=price, value=370.0000
Key=weight, value=1.0000
Key=meta_title, value=RIP2/RIPK2 Antibody
Key=meta_description, value=Boster Bio Anti-RIP2/RIPK2 Antibody Picoband® catalog # A011954-1. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with human.
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Key=url_key, value=anti-rip2-ripk2-picoband-trade-antibody-a00818-2-boster
Key=url_path, value=anti-fibrinogen-alpha-chain-picoband-trade-antibody-a00816-1-boster
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Key=image_label, value=Figure 1. Western blot analysis of RIP2/RIPK2 using anti-RIP2/RIPK2 antibody (A00818-2).
Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30
Key=small_image_label, value=Figure 1. Western blot analysis of RIP2/RIPK2 using anti-RIP2/RIPK2 antibody (A00818-2).
Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30
Key=thumbnail_label, value=Figure 1. Western blot analysis of RIP2/RIPK2 using anti-RIP2/RIPK2 antibody (A00818-2).
Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30
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Key=size, value=100 μg/vial
Key=protein_name, value=Fibrinogen alpha chain
Key=gene_full_name, value=fibrinogen alpha chain
Key=uniprot_id, value=O43353
Key=reconstitution, value=Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Key=applications, value=ELISA, Flow Cytometry, WB
Key=reactivity, value=Human
Key=form, value=Lyophilized
Key=concentration, value=Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Key=cross_reactivity, value=No cross-reactivity with other proteins.
Key=recommended_detection_systems, value=Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.
Key=predicted_reactivity
Key=source_company, value=Boster A00818-2
Key=isotype, value=Rabbit IgG
Key=molecular_weight, value=94973 MW
Key=sample_size_available, value=30ug for $99, contact us for details
Key=related_product_skus, value=B0001-5,AR1156,AR0146
Key=product_category, value=Primary Antibodies
Key=research_category, value=Signal Transduction
Key=clonality, value=Polyclonal
Key=swatch_image, value=/a/0/a00818-2-ripk2-primary-antibodies-wb-testing-1.jpg
Key=rating_value, value=100
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Key=cj_related_products, value=Anemia:EK0812|PROTQ29983^Growth Retardation:PA1895^Ossification:A09618T3^Stem Cell Maintenance:PB9133|A00313
Key=description, value=Boster Bio Anti-RIP2/RIPK2 Antibody Picoband® catalog # A00818-2. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=short_description, value=Boster Bio Anti-RIP2/RIPK2 Antibody Picoband® catalog # A00818-2. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=meta_keyword, value=Anti-RIP2/RIPK2 Antibody Picoband®
Key=contents, value=Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
Key=background, value=RIPK2(Receptor-interacting serine/threonine-protein kinase 2), also known as CARD3, CARDIAK, RICK, RIP2, is anenzymethat in humans is encoded by theRIPK2gene.It has 540-amino acid protein in length.Northern blot analysis revealed that RICK is expressed in various human tissues as 2.5- and 1.8-kb mRNAs that differ due to alternative polyadenylation. RICK is a novel kinase that may regulate apoptosis induced by the FAS receptor pathway. This gene encodes a member of the receptor-interacting protein(RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminalcaspase recruitment domain(CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator ofNF-kappa Band inducer of apoptosis in response to various stimuli, CARDIAK(CARD-containing ICE-associated kinase) specifically interacted with the CARD of ICE/caspase-1, and this interaction correlated with the processing of pro-caspase-1 and the formation of the active caspase-1 p20 subunit.
Key=gene_name, value=RIPK2
Key=synonyms, value=Fibrinogen alpha chain; FGA
Key=application_details, value=Western blot, 0.25-0.5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Key=subcellular_localization, value=Secreted.
Key=tissue_specificity, value=Detected in blood plasma (at protein level).
Key=application_notes, value=Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Key=competitor_equivalent_skus, value=sc 18027|sc 271035|sc 18029|sc 33581|sc 271018|sc 271017|sc 33580|sc 53284|sc 33917|sc 33916|sc 18026|sc 166968|sc 51892|sc 398806|sc 65966|sc 51898|sc 69775|sc 51896|sc 51895|sc 51894|sc 51891|sc 57508|sc 51889
Key=immunogen, value=E.coli-derived human RIP2/RIPK2 recombinant protein (Position: Y15-M540).
Key=purification, value=Immunogen affinity purified.
Key=storage, value=At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
Key=custom_attribute_1, value=61 kDa
Key=custom_attribute_2, value=WB: human K562 whole cell, human PC-3 whole cell, human Daudi whole cell, human T-47D whole cell, human U251 whole cell
FCM: Caco-2 cell
Key=protein_function, value=Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways.
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