Product Info Summary
SKU: | A09743 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-RIOK2 Antibody
SKU/Catalog Number
A09743
Size
100ul
Form
Liquid
Description
Boster Bio Anti-RIOK2 Antibody catalog # A09743. Tested in WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-RIOK2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09743)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human RFWD3.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A09743 is reactive to RIOK2 in Human
Applications
A09743 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
63283 MW
Background of RIOK2
E3 ubiquitin-protein ligase that mediates the ubiquitination of p53/TP53 in the late response to DNA damage, and acts as a positive regulator of p53/TP53 stability, thereby regulating the G1/S DNA damage checkpoint. May act by catalyzing the formation of short polyubiquitin chains on p53/TP53 that are not targeted to the proteasome. In response to ionizing radiation, interacts with MDM2 and enhances p53/TP53 ubiquitination, possibly by restricting MDM2 from extending polyubiquitin chains on ubiquitinated p53/TP53. Plays a role in RPA-mediated DNA damage signaling and repair.
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Ota T., Nat. Genet. 36:40-45(2004).
Matsuoka S., Science 316:1160-1166(2007).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
Validation Images & Assay Conditions
![a09743 anti riok2 antibody wb testing 1 a09743 anti riok2 antibody wb testing 1](https://www.bosterbio.com/media/catalog/product/a/0/a09743-anti-riok2-antibody-wb-testing-1.jpg)
Click image to see more details
Western blot analysis of extracts of various cell lines, using RIOK2 antibody.
Protein Target Info & Infographic
Gene/Protein Information For RIOK2 (Source: Uniprot.org, NCBI)
Gene Name
RIOK2
Full Name
Serine/threonine-protein kinase RIO2
Weight
63283 MW
Superfamily
protein kinase superfamily
Alternative Names
EC 2.7.11.1; FLJ11159; RIO kinase 2 (yeast); RIO kinase 2; RIO2; serine/threonine-protein kinase RIO2 RIOK2 RIO2 RIO kinase 2 serine/threonine-protein kinase RIO2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on RIOK2, check out the RIOK2 Infographic
![RIOK2 infographic](/media/images/gene-infographic-example.jpg)
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for RIOK2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-RIOK2 Antibody (A09743)
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No publications found for A09743
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