Product Info Summary
SKU: | A02596 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | IF, ICC, WB |
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Product info
Product Name
Anti-Ras-related protein Rap-1b RAP1B Antibody
SKU/Catalog Number
A02596
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Ras-related protein Rap-1b RAP1B Antibody catalog # A02596. Tested in WB,ICC/IF applications. This antibody reacts with Human,Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Ras-related protein Rap-1b RAP1B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02596)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human CDK5R1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02596 is reactive to RAP1B in Human, Mouse
Applications
A02596 is guaranteed for IF, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
20825 MW
Background of RAP1B
p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution.
Tsai L.-H., Nature 371:419-423(1994).
Patrick G.N., Nature 402:615-622(1999).
Kesavapany S., J. Neurosci. 24:4421-4431(2004).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
ICC/IF: 1:50-1:200
Validation Images & Assay Conditions
![a02596 anti ras related protein rap 1b rap1b antibody wb testing 1 a02596 anti ras related protein rap 1b rap1b antibody wb testing 1](https://www.bosterbio.com/media/catalog/product/a/0/a02596-anti-ras-related-protein-rap-1b-rap1b-antibody-wb-testing-1.jpg)
Click image to see more details
Figure 1. Western blotting validation for Anti-Ras-related protein Rap-1b RAP1B Antibody A02596
Western blot analysis of extracts of various cell linesProtein Target Info & Infographic
Gene/Protein Information For RAP1B (Source: Uniprot.org, NCBI)
Gene Name
RAP1B
Full Name
Ras-related protein Rap-1b
Weight
20825 MW
Superfamily
small GTPase superfamily
Alternative Names
DKFZp586H0723; GTP-binding protein smg p21B; KREV; K-REV; RAL1B; Rap1B; RAP1B, member of RAS oncogene family; Ras family small GTP binding protein RAP1B; RAS-related protein RAP1B; ras-related protein Rap-1b; small GTP binding protein RAP1B K-REV, RAL1B RAP1B, member of RAS oncogene family ras-related protein Rap-1b|GTP-binding protein smg p21B|RAS-related protein RAP1B|Ras family small GTP binding protein RAP1B|small GTP binding protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on RAP1B, check out the RAP1B Infographic
![RAP1B infographic](/media/images/gene-infographic-example.jpg)
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for RAP1B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Ras-related protein Rap-1b RAP1B Antibody (A02596)
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