Anti-R-RAS2 Purified Monoclonal Antibody

Product Name

Anti-R-RAS2 Purified Monoclonal Antibody

View all TC21/R-Ras2 Antibodies

SKU/Catalog Number

M04117

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-R-RAS2 Purified Monoclonal Antibody (Catalog# M04117). Tested in Flow Cytometry, WB, ELISA, ICC application(s). This antibody reacts with Human.

Storage & Handling

Store at 2-8°C. Do not freeze.

Cite This Product

Anti-R-RAS2 Purified Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M04117)

Host

Mouse

Contents

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Clonality

Monoclonal

Clone Number

EM-50

Isotype

Mouse IgG1 kappa

Immunogen

Human TC21. The mouse monoclonal antibody EM-50 recognizes R-Ras2 / TC21 protein (intracellular antigen) and does not react with R-Ras1, H-Ras, K-Ras, and N-Ras.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

This antibody does not cross-react with Thy-1.1 alloantigen.

Reactive Species

M04117 is reactive to RRAS2 in Human

Reconstitution

Observed Molecular Weight

42 kDa

Calculated molecular weight

23400 MW

Background of TC21/R-Ras2

R-Ras2 / TC21 is the only member of R-Ras family of small GTPases that shows transforming activities similar to H-Ras, N-Ras, and K-Ras, and it is also structurally similar to them. R-Ras2 seems to play an important role in activating signal transduction pathways that control cell proliferation. Its mutations are associated with the growth of certain tumors, but also overexpression of the wild type form of R-Ras2 has been frequently detected in various carcinomas. Pseudogenes of R-Ras2 gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

M04117 is guaranteed for ELISA, Flow Cytometry, ICC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Flow cytometry: 1-4 μg/ml. Intracellular staining.

Validation Images & Assay Conditions

Gene/Protein Information For RRAS2 (Source: Uniprot.org, NCBI)

Alternative Names

TC21, RRAS2 RRAS2 NS12, TC21 RAS related 2 ras-related protein R-Ras2|ras-like protein TC21|related RAS viral (r-ras) oncogene homolog 2|teratocarcinoma oncogene

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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