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Key=sku, value=A00640
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Key=created_at, value=2020-03-11 06:18:51
Key=updated_at, value=2024-09-26 01:03:52
Key=mst_search_weight, value=0
Key=status, value=Enabled
Key=name, value=Anti-Protein jagged-1 JAG1 Antibody
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Key=is_recurring, value=No
Key=visibility, value=Catalog, Search
Key=tax_class_id, value=Taxable Goods
Key=conjugate
Key=featured, value=No
Key=featured_image, value=Yes
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Key=template, value=antibodies
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Key=price, value=449.0000
Key=weight, value=1.0000
Key=meta_title, value=Anti-Protein jagged-1 JAG1 Antibody
Key=meta_description, value=Boster Bio Anti-Protein jagged-1 JAG1 Antibody (Catalog # A00640). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat. Supplied as 0.1 mg in Liquid form antibody.
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Key=url_key, value=anti-protein-jagged-1-jag1-antibody-a00640-boster
Key=url_path, value=anti-il-8-antibody-a00423-boster
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Key=msrp_display_actual_price_type, value=Use config
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Key=size, value=0.1 mg
Key=protein_name, value=Jagged 1
Key=gene_full_name, value=Jagged 1
Key=uniprot_id, value=P78504
Key=sensitivity
Key=applications, value=ELISA, IF, IHC-P, WB
Key=reactivity, value=Human, Mouse, Rat
Key=form, value=Liquid
Key=concentration, value=1 mg/mL
Key=cross_reactivity, value=JAG1 antibody is human, mouse and rat reactive. At least two isoforms of JAG1 are known to exist; this antibody will detect both isoforms.
Key=clone_number
Key=predicted_reactivity, value=Bovine, Chicken, Pig
Key=source_company, value=Prosci 8059; Cost: 249
Key=isotype, value=IgG
Key=molecular_weight, value=133799 MW
Key=sample_size_available, value=25ug for $99, contact us for details
Key=related_product_skus, value=EK0413,PB9621,PROTP10145,PROTP10145-1,PROTP10145-2,PROTP10145-3,PROTP19874,PROTP26894,PROTP41324,PROTP67813
Key=product_category, value=Primary Antibodies
Key=research_category, value=Cancer, Cell Cycle, Stem Cells
Key=clonality, value=Polyclonal
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Key=rating_value, value=100
Key=review_count, value=4
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Key=cj_related_products, value=Alagille Syndrome:A00518-2|A00518-1^Cell Fate Specification:PA2229^Lateral Inhibition:M01206-1^Liver Development:R00804^Pulmonary Stenosis:DZ04652
Key=description, value=Boster Bio Anti-Protein jagged-1 JAG1 Antibody (Catalog # A00640). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Key=short_description, value=Boster Bio Anti-Protein jagged-1 JAG1 Antibody (Catalog # A00640). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Key=meta_keyword, value=Anti-Protein jagged-1 JAG1 Antibody
Key=contents, value=JAG1 antibody is supplied in PBS containing 0.02% sodium azide.
Key=background, value=The LIN-12/Notch family of transmembrane receptors plays a central role in development by regulating cell fate decisions (1). Ligands for Notch include JAG1, JAG2 and Delta. JAG1 is one of the DSL (Delta, Serrate, Lag2) transmembrane proteins that can activate Notch. It is involved in mammalian cardiovascular development and in cell-fate decisions during hematopoiesis (1,2). JAG1 is widely expressed in adult and fetal tissues and the mutation of the JAG1 gene is associated with Familial Tetrology of Fallot (3). JAG1 expression is associated with prostate cancer metastasis and is up-regulated in cervical squamous cell carcinoma (4,5).
Key=gene_name, value=JAG1
Key=synonyms, value=Jagged 1, AGS, AHD, AWS, CD339, HJ1, JAGL1
Key=application_details, value=JAG1 antibody can be used for detection of JAG1 by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Key=subcellular_localization, value=Membrane; Single-pass type I membrane protein.
Key=tissue_specificity, value=Widely expressed in adult and fetal tissues. In cervix epithelium expressed in undifferentiated subcolumnar reserve cells and squamous metaplasia. Expression is up-regulated in cervical squamous cell carcinoma. Expressed in bone marrow cell line HS-27a which supports the long-term maintenance of immature progenitor cells.
Key=protein_function, value=Ligand for multiple Notch receptors and involved in the mediation of Notch signaling (PubMed:18660822, PubMed:20437614). May be involved in cell-fate decisions during hematopoiesis (PubMed:9462510). Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). Enhances fibroblast growth factor-induced angiogenesis (in vitro).
Key=application_notes
Key=description_before_attributes
Key=competitor_equivalent_skus, value=sc 25342|sc 55462|sc 7165|sc 4600|sc 73321|sc 7922|sc 1269|sc 376750|sc 8427|sc 7302|sc 52870|sc 101499|sc 32817|sc 71367
Key=immunogen, value=JAG1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human JAG1. The immunogen is located within the last 50 amino acids of JAG1.
Key=purification, value=JAG1 antibody is affinity chromatography purified via peptide column.
Key=storage, value=JAG1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Key=custom_attribute_1, value=68 kDa
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