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Key=sku, value=A00577
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Key=created_at, value=2021-04-04 18:12:13
Key=updated_at, value=2024-10-31 05:02:22
Key=mst_search_weight, value=0
Key=status, value=Enabled
Key=name, value=Anti-Phospho-CREB(S133) Antibody
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Key=host, value=Rabbit
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Key=price, value=299.0000
Key=weight, value=1.0000
Key=meta_title, value=Anti-Phospho-CREB(S133) Antibody | Boster
Key=meta_description, value=Boster Bio Anti-Phospho-CREB(S133) Antibody (Catalog # A00577). Tested in IHC-P-Leica, IF, WB application(s). This antibody reacts with Human.
Key=image, value=/a/0/a00489-2-anti-mertk-antibody-if-testing-1_1.jpg
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Key=url_key, value=anti-phospho-crebs133-antibody-a00577-boster
Key=url_path, value=anti-hcg-beta-pregnancy-choriocarcinoma-marker-antibody-m30373-boster
Key=options_container, value=Block after Info Column
Key=image_label, value= Fluorescent image of U251 cell stained with MERTK Antibody.U251 cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with MERTK primary antibody (1:25, 1 h at 37℃). For secondary antibody, Alexa Fluor® 48
Key=small_image_label, value= Fluorescent image of U251 cell stained with MERTK Antibody.U251 cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with MERTK primary antibody (1:25, 1 h at 37℃). For secondary antibody, Alexa Fluor® 48
Key=thumbnail_label, value= Fluorescent image of U251 cell stained with MERTK Antibody.U251 cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with MERTK primary antibody (1:25, 1 h at 37℃). For secondary antibody, Alexa Fluor® 48
Key=msrp_display_actual_price_type, value=Use config
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Key=size, value=80 µl
Key=protein_name, value=Cluster of differentiation 14
Key=gene_full_name, value=Choriogonadotropin subunit beta
Key=uniprot_id, value=P16220
Key=sensitivity
Key=applications, value=IF, WB, IHC-P-Leica
Key=reactivity, value=Human
Key=form, value=Liquid
Key=cross_reactivity, value=No cross reactivity with other proteins.
Key=recommended_detection_systems, value=Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
Key=predicted_reactivity, value=C. elegans
Key=source_company, value=Abcepta AP3077a-ev: 75| AP3077a: 192.5
Key=isotype, value=Rabbit IgG
Key=molecular_weight, value=35136 Da
Key=sample_size_available, value=20ug for $99, contact us for details
Key=related_product_skus, value=MA1111
Key=product_category, value=Primary Antibodies
Key=research_category, value=Apoptosis, Cancer, Cell Biology, Host-Virus Interaction, Immunology, Microbiology, Neuroscience, Signal Transduction, Viral process
Key=clonality, value=Polyclonal
Key=swatch_image, value=/a/0/a00489-2-anti-mertk-antibody-if-testing-1_1.jpg
Key=rating_value, value=95
Key=review_count, value=2
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Key=cj_related_products, value=Long-term Memory:EK0309|EK0307-PR|EZ0309|PB9100|P00577-1^Mood Disorders:A01677-Dyl550
Key=description, value=Boster Bio Anti-Phospho-CREB(S133) Antibody (Catalog # A00577). Tested in IHC-P-Leica, IF, WB application(s). This antibody reacts with Human.
Key=short_description, value=Boster Bio Anti-Phospho-CREB(S133) Antibody (Catalog # A00577). Tested in IHC-P-Leica, IF, WB application(s). This antibody reacts with Human.
Key=meta_keyword, value=Anti-Phospho-CREB (S133) Antibody
Key=contents, value=Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Key=background, value=CREB is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, (CRE), a sequence present in many viral and cellular promoters. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway.
Key=gene_name, value=CREB1
Key=synonyms, value=Cyclic AMP-responsive element-binding protein 1, CREB-1, cAMP-responsive element-binding protein 1, CREB1
Key=application_details, value=WB: 1:500
IHC-P-Leica: 1:500
Key=subcellular_localization, value=Nucleus {ECO:0000255|PROSITE-ProRule:PRU00312, ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:12552083}
Key=tissue_specificity, value=Liver (at protein level).
Key=protein_function, value=Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters (By similarity). Transcription activation is enhanced by the TORC coactivators which act independently of Ser-119 phosphorylation (PubMed:14536081). Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells (By similarity). Regulates the expression of apoptotic and inflammatory response factors in cardiomyocytes in response to ERFE-mediated activation of AKT signaling (By similarity).
Key=competitor_equivalent_skus, value=sc 23928|sc 59873|sc 59872|sc 52390
Key=immunogen, value=This CREB Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S133 of human CREB.
Key=purification, value=This antibody is purified through a protein A column, followed by peptide affinity purification.
Key=storage, value=Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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