Product Info Summary
SKU: | A01677-Dyl550 |
---|---|
Size: | 100 μg/vial |
Reactive Species: | Human |
Host: | Rabbit |
Application: | Flow Cytometry |
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Product info
Product Name
Anti-Human CCKBR DyLight® 550 conjugated Antibody
View all Cholecystokinin-B R/CCKBR Antibodies
SKU/Catalog Number
A01677-Dyl550
Size
100 μg/vial
Form
Liquid
Description
Boster Bio Anti-Human CCKBR DyLight® 550 conjugated Antibody catalog # A01677-Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.
Storage & Handling
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Cite This Product
Anti-Human CCKBR DyLight® 550 conjugated Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01677-Dyl550)
Host
Rabbit
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human CCKBR, which shares 80% and 90% amino acid (aa) sequence identity with mouse and rat CCKBR, respectively.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins.
Reactive Species
A01677-Dyl550 is reactive to CCKBR in Human
Reconstitution
Observed Molecular Weight
39 kDa
Calculated molecular weight
48.419kDa
Background of Cholecystokinin-B R/CCKBR
The cholecystokinin B receptor, also known as CCKBR or CCK2, is a protein that in humans is encoded by the CCKBR gene. This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. Alternative splicing results in multiple transcript variants. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A01677-Dyl550 is guaranteed for Flow Cytometry Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Flow Cytometry (Fixed), 1-3μg/1x106 cells
Validation Images & Assay Conditions
Click image to see more details
Boster Kit Box
Protein Target Info & Infographic
Gene/Protein Information For CCKBR (Source: Uniprot.org, NCBI)
Gene Name
CCKBR
Full Name
Gastrin/cholecystokinin type B receptor
Weight
48.419kDa
Superfamily
G-protein coupled receptor 1 family
Alternative Names
Gastrin/cholecystokinin type B receptor; CCK-B receptor; CCK-BR; Cholecystokinin-2 receptor; CCK2-R; CCKBR; CCKRB CCKBR CCK-B, CCK2R, GASR cholecystokinin B receptor gastrin/cholecystokinin type B receptor|CCK-B receptor|CCK2 receptor|cholecystokinin-2 receptor|gastrin receptor
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CCKBR, check out the CCKBR Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CCKBR: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Human CCKBR DyLight® 550 conjugated Antibody (A01677-Dyl550)
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Customer Reviews
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Customer Q&As
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4 Customer Q&As for Anti-Human CCKBR DyLight® 550 conjugated Antibody
Question
Is a blocking peptide available for product anti-Human CCKBR DyLight® 550 conjugated antibody (A01677-Dyl550)?
Verified Customer
Verified customer
Asked: 2019-11-11
Answer
We do provide the blocking peptide for product anti-Human CCKBR DyLight® 550 conjugated antibody (A01677-Dyl550). If you would like to place an order for it please contact [email protected] and make a special request.
Boster Scientific Support
Answered: 2019-11-11
Question
We are currently using anti-Human CCKBR DyLight® 550 conjugated antibody A01677-Dyl550 for human tissue, and we are satisfied with the Flow Cytometry results. The species of reactivity given in the datasheet says human. Is it likely that the antibody can work on canine tissues as well?
Verified Customer
Verified customer
Asked: 2019-06-14
Answer
The anti-Human CCKBR DyLight® 550 conjugated antibody (A01677-Dyl550) has not been validated for cross reactivity specifically with canine tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in canine you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2019-06-14
Question
My lab would like to test anti-Human CCKBR DyLight® 550 conjugated antibody A01677-Dyl550 on human colon cancer for research purposes, then I may be interested in using anti-Human CCKBR DyLight® 550 conjugated antibody A01677-Dyl550 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?
Verified Customer
Verified customer
Asked: 2017-07-31
Answer
The products we sell, including anti-Human CCKBR DyLight® 550 conjugated antibody A01677-Dyl550, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.
Boster Scientific Support
Answered: 2017-07-31
Question
Does anti-Human CCKBR DyLight® 550 conjugated antibody A01677-Dyl550 work for Flow Cytometry with colon cancer?
G. Edwards
Verified customer
Asked: 2014-12-23
Answer
According to the expression profile of colon cancer, CCKBR is highly expressed in colon cancer. So, it is likely that anti-Human CCKBR DyLight® 550 conjugated antibody A01677-Dyl550 will work for Flow Cytometry with colon cancer.
Boster Scientific Support
Answered: 2014-12-23