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Product Info Summary
| SKU: | A02018 |
|---|---|
| Size: | 100 µl |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | IHC, WB |
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Product info
Product Name
Anti-NUMA1/Numa Antibody
SKU/Catalog Number
A02018
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-NUMA1/Numa Antibody (Catalog # A02018). Tested in WB, IHC applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-NUMA1/Numa Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02018)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human NUMA1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02018 is reactive to NUMA1 in Human
Reconstitution
Calculated molecular weight
238260 MW
Background of NuMA
Highly abundant component of the nuclear matrix where it may serve a non-mitotic structural role, occupies the majority if the nuclear volume. Required for maintenance and establishment of the mitotic spindle poles, functionning as a tether linking bulk microtubules of the spindle to centrosomes. May be involved in coordination of the alignment of the mitotic spindle to the cellular polarity axis, which is a prerequisite for asymmetric cell divisions.
Yang C.H., J. Cell Biol. 116:1303-1317(1992).
Compton D.A., J. Cell Biol. 116:1395-1408(1992).
Maekawa T., J. Cell Sci. 105:589-600(1993).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A02018 is guaranteed for IHC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Validation Images & Assay Conditions
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Western blot analysis of extracts from A549 cells, using NUMA1 antibody A02018.
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Immunohistochemistry analysis of paraffin-embedded human testis tissue using NUMA1 antibody A02018.
Protein Target Info & Infographic
Gene/Protein Information For NUMA1 (Source: Uniprot.org, NCBI)
Gene Name
NUMA1
Full Name
Nuclear mitotic apparatus protein 1
Weight
238260 MW
Alternative Names
Nuclear mitotic apparatus protein 1 ;NuMA protein ;Nuclear matrix protein-22;NMP-22;SP-H antigen ;NUMA1 ;NMP22 , NUMA ; NUMA1 NMP-22, NUMA nuclear mitotic apparatus protein 1 nuclear mitotic apparatus protein 1|SP-H |centrophilin stabilizes mitotic spindle in mitotic cells|nuclear matrix protein-22|structural nuclear protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on NUMA1, check out the NUMA1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for NUMA1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-NUMA1/Numa Antibody (A02018)
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No publications found for A02018
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