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Product Info Summary
| SKU: | A02478 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, IF, ICC, WB |
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Product info
Product Name
Anti-Nudel NDEL1 Antibody
SKU/Catalog Number
A02478
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Nudel NDEL1 Antibody (Catalog # A02478). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse.
Storage & Handling
Nudel antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Nudel NDEL1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02478)
Host
Rabbit
Contents
Nudel Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Nudel antibody was raised against a peptide corresponding to 15 amino acids near the amino terminus of human Nudel. The immunogen is located within the first 50 amino acids of Nudel.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Betatrophin antibody is human, mouse and rat reactive. At least three isoforms of Betatrophin are known to exist; this antibody will detect the two largest isoforms.
Reactive Species
A02478 is reactive to NDEL1 in Human, Mouse
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
38375 MW
Background of Nudel
Nudel was initially discovered as a protein homologous to Aspergillus NUDE and that associated with Lis1 and polyprotein complex cytoplasmic dynein, both of which have been linked to neuronal development and migration. It was later shown to be a substrate of cdk5, a kinase known to be critical during neuronal migration; phosphorylation of Nudel by cdk5 affects its localization in neurons and affects neuritic morphology. It is thought that together with Lis1, Nudel regulates cytoplasmic dynein, a large polyprotein complex, in neuronal migration and mitosis through direct interactions. Similar interactions are thought to also play a role in membrane traffic in other cells as disruption of Nudel expression through RNA interference perturbed normal endomembrane flux and resulted in the fragmentation of the Golgi apparatus.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A02478 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Nudel antibody can be used for detection of Nudel by Western blot at 0.5 - 2 μg/mL. Antibody can also be used for immunocytochemistry starting at 2 μg/mL. For immunofluorescence start at 10 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of Nudel in Jurkat whole cell lysate with Nudel antibody at (A) 0.5
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Immunocytochemistry of Nudel in Jurkat cells with Nudel antibody at 2 μg/mL.
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Immunofluorescence of Nudel in Jurkat cells with Nudel antibody at 10 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For NDEL1 (Source: Uniprot.org, NCBI)
Gene Name
NDEL1
Full Name
Nuclear distribution protein nudE-like 1
Weight
38375 MW
Superfamily
nudE family
Alternative Names
EOPA, NDE2, NUDEL, MITAP1, NDE1L1, EOPA, Nuclear distribution protein nudE-like 1, Mitosin-associated protein 1, Protein Nudel NDEL1 EOPA, MITAP1, NDE1L1, NDE2, NUDEL nudE neurodevelopment protein 1 like 1 nuclear distribution protein nudE-like 1|endooligopeptidase A|mitosin-associated protein 1|mitosin-associated protein MITAP1|nudE nuclear distribution E homolog-like 1|nudE nuclear distribution gene E homolog-like 1|protein Nudel
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on NDEL1, check out the NDEL1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for NDEL1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Nudel NDEL1 Antibody (A02478)
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