Anti-NMDAR2A/GRIN2A Antibody

Product Name

Anti-NMDAR2A/GRIN2A Antibody

View all GRIN2A Antibodies

SKU/Catalog Number

PA1058-1

Size

100μg/vial

Form

Lyophilized

Description

Boster Bio Anti-NMDAR2A/GRIN2A Antibody catalog # PA1058-1. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-NMDAR2A/GRIN2A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1058-1)

Host

Rabbit

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Clonality

Polyclonal

Clone Number

G9

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human NMDAR2A, different from the related mouse sequence by three amino acids, and from the related rat sequence by four amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins

Reactive Species

PA1058-1 is reactive to GRIN2A in Human, Mouse, Rat

Applications

PA1058-1 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

42 kDa

Calculated molecular weight

165283 MW

Background of GRIN2A

GRIN2A is also known as N-methyl-D-aspartate receptor channel, subunit epsilon-1 (NMDAR2A). This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Rat, Human, Mouse, By Heat
Western blot, 0.1-0.5μg/ml, Mouse, Rat, Human

Validation Images & Assay Conditions

Click image to see more details

Anti-NMDAR2A antibody, PA1058-1, Western blotting
All lanes: Anti NMDAR2A (PA1058-1) at 0.5ug/ml
Lane 1: Rat Brain Tissue Lysate at 50ug
Lane 2: Mouse Brain Tissue Lysate at 50ug
Predicted bind size: 165KD
Observed bind size: 165KD

Click image to see more details

Anti-NMDAR2A antibody, PA1058-1, IHC(P)
IHC(P): Rat Brain Tissue

Gene/Protein Information For GRIN2A (Source: Uniprot.org, NCBI)

Alternative Names

glutamate receptor, ionotropic, N-methyl D-aspartate 2A; hNR2A; NMDA receptor subtype 2A; N-methyl D-aspartate receptor subtype 2A; N-methyl-D-aspartate receptor subunit 2A; subunit epsilon-1 GRIN2A EPND, FESD, GluN2A, LKS, NMDAR2A, NR2A glutamate ionotropic receptor NMDA type subunit 2A glutamate receptor ionotropic, NMDA 2A|N-methyl D-aspartate receptor subtype 2A|N-methyl-D-aspartate receptor channel, subunit epsilon-1|N-methyl-D-aspartate receptor subunit 2A|glutamate ionotropic receptor NMDA 2A|glutamate receptor, ionotropic, N-methyl D-aspartate 2A

For more info on GRIN2A, check out the GRIN2A Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for GRIN2A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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