Anti-NMDAR2A/GRIN2A Antibody Picoband®

Product Name

Anti-NMDAR2A/GRIN2A Antibody Picoband®

View all GRIN2A Antibodies

SKU/Catalog Number

PB9335

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-NMDAR2A/GRIN2A Antibody Picoband® catalog # PB9335. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-NMDAR2A/GRIN2A Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9335)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human NMDAR2A recombinant protein (Position: D958-R1300). Human NMDAR2A shares 89% and 90% amino acid (aa) sequence identity with mouse and rat NMDAR2A, respectively.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PB9335 is reactive to GRIN2A in Human, Mouse, Rat

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

165 kDa

Calculated molecular weight

165283 MW

Background of GRIN2A

GRIN2A is also known as N-methyl-D-aspartate receptor channel, subunit epsilon-1 (NMDAR2A). This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PB9335 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Mouse, Rat, Human

Positive Control

WB: Rat Brain Tissue, Mouse Brain Tissue

Validation Images & Assay Conditions

Gene/Protein Information For GRIN2A (Source: Uniprot.org, NCBI)

Alternative Names

Glutamate receptor ionotropic, NMDA 2A;GluN2A;Glutamate [NMDA] receptor subunit epsilon-1;N-methyl D-aspartate receptor subtype 2A;NMDAR2A;NR2A;hNR2A;GRIN2A;NMDAR2A; GRIN2A EPND, FESD, GluN2A, LKS, NMDAR2A, NR2A glutamate ionotropic receptor NMDA type subunit 2A glutamate receptor ionotropic, NMDA 2A|N-methyl D-aspartate receptor subtype 2A|N-methyl-D-aspartate receptor channel, subunit epsilon-1|N-methyl-D-aspartate receptor subunit 2A|glutamate ionotropic receptor NMDA 2A|glutamate receptor, ionotropic, N-methyl D-aspartate 2A

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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