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Product Info Summary
| SKU: | M03630 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Mouse |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-Ms Blnk Purified Rabbit Monoclonal Antibody
SKU/Catalog Number
M03630
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Ms Blnk Purified Rabbit Monoclonal Antibody (Catalog# M03630). Tested in WB application(s). This antibody reacts with Mouse.
Storage & Handling
Store at 2-8°C. Do not freeze.
Cite This Product
Anti-Ms Blnk Purified Rabbit Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M03630)
Host
Rabbit
Contents
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Clonality
Monoclonal
Clone Number
PAb (411)
Isotype
Rabbit polyclonal
Immunogen
A fusion protein representing amino acids 171-356 of human BLNK. The polyclonal antibody reacts with mouse SLP65 / BLNK, a cytosolic adaptor protein identified as two phosphoproteins migrating at 68 and 70 kDa in SDS/PAGE (alternatively spliced forms of human SLP65).
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
This antibody does not cross-react with Thy-1.1 alloantigen.
Reactive Species
M03630 is reactive to BLNK in Mouse
Reconstitution
Observed Molecular Weight
42 kDa
Calculated molecular weight
50466 MW
Background of Blnk
SLP65 / BLNK (SH2 domain-containing leukocyte-specific phosphoprotein of 65 kDa; B cell linker protein), also known as BASH, is an adaptor protein that plays key role in B cell activation initiated by cross-linking the B cell receptor (BCR). Phosphorylated by Syk tyrosine kinase, SLP65 serves as a scaffold for Btk tyrosine kinase, Vav1 guanine nucleotide exchange factor, phospholipase C gamma2, as well as Grb2 and Nck adaptor proteins; thus represents a central linker protein that bridges the BCR-associated kinases with a multitude of signaling pathways.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M03630 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blotting: Reducing conditions.
Validation Images & Assay Conditions
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Figure 1. Western blotting validation for Anti-Ms Blnk Purified Rabbit Monoclonal Antibody M03630
Western blotting analysis (reducing conditions) of whole cell lysate of Sp2/0 mouse myeloma cell line using polyclonal anti-mouse SLP65 / BLNK antibody.Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For BLNK (Source: Uniprot.org, NCBI)
Gene Name
BLNK
Full Name
B-cell linker protein
Weight
50466 MW
Alternative Names
SLP65, BASH, Ly57 Blnk|BA, BASH, BC, BL, Bca, Ly-5, Ly-57, Ly5, Ly57, Lyw-57, SLP, SLP-65|B cell linker|B-cell linker protein|B-cell adapter containing a SH2 domain protein|B-cell adapter containing a Src homology 2 domain protein|cytoplasmic adapter protein|lymphocyte 57|src homology 2 domain-containing leukocyte protein of 65 kDa
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on BLNK, check out the BLNK Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for BLNK: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Ms Blnk Purified Rabbit Monoclonal Antibody (M03630)
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No publications found for M03630
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