Anti-Mouse Ctr9 Antibody (C-term)

CTR9 antibody

Boster Bio Anti-Mouse Ctr9 Antibody (C-term) (Catalog # A05192). Tested in IF, IHC-P, WB application(s). This antibody reacts with Human, Mouse.

Product Info Summary

SKU: A05192
Size: 80 µl
Reactive Species: Human, Mouse
Host: Rabbit
Application: IF, IHC-P, WB

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Product Name

Anti-Mouse Ctr9 Antibody (C-term)

View all CTR9 Antibodies

SKU/Catalog Number

A05192

Size

80 µl

Description

Boster Bio Anti-Mouse Ctr9 Antibody (C-term) (Catalog # A05192). Tested in IF, IHC-P, WB application(s). This antibody reacts with Human, Mouse.

Storage & Handling

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Cite This Product

Anti-Mouse Ctr9 Antibody (C-term) (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05192)

Host

Rabbit

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

This Mouse Ctr9 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1022-1056 amino acids from the C-terminal region of Mouse Ctr9.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A05192 is reactive to CTR9 in Human, Mouse

Applications

A05192 is guaranteed for IF, IHC-P, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

133408 Da

Background of CTR9

Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non- phosphorylated and 'Ser-2'- and 'Ser-5'-phosphorylated forms and is involved in transcriptional elongation, acting both indepentently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. PAF1C is required for transcription of Hox and Wnt target genes. PAF1C is involved in hematopoiesis and stimulates transcriptional activity of KMT2A/MLL1. PAF1C is involved in histone modifications such as ubiquitination of histone H2B and methylation on histone H3 'Lys- 4' (H3K4me3). PAF1C recruits the RNF20/40 E3 ubiquitin-protein ligase complex and the E2 enzyme UBE2A or UBE2B to chromatin which mediate monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1); UB2A/B-mediated H2B ubiquitination is proposed to be coupled to transcription. PAF1C is involved in mRNA 3' end formation probably through association with cleavage and poly(A) factors. Required for mono- and trimethylation on histone H3 'Lys- 4' (H3K4me3) and dimethylation on histone H3 'Lys-79' (H3K4me3). Required for Hox gene transcription (By similarity). Required for the trimethylation of histone H3 'Lys-4' (H3K4me3) on genes involved in stem cell pluripotency; this function is synergistic with CXXC1 indicative for an involvement of the SET1 complex. Involved in transcriptional regulation of IL6-responsive genes and in JAK-STAT pathway; may regulate DNA-association of STAT3.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

IF: 1:25
WB: 1:1000
IHC-P: 1:25

Validation Images & Assay Conditions

Gene/Protein Information For CTR9 (Source: Uniprot.org, NCBI)

Gene Name

CTR9

Full Name

RNA polymerase-associated protein CTR9 homolog

Weight

133408 Da

Alternative Names

Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae); KIAA0155SH2 domain-binding protein 1; p150TSP; RNA polymerase-associated protein CTR9 homolog; SH2 domain binding protein 1 (tetratricopeptide repeat containing); SH2BP1p150; TPR-containing, SH2-binding phosphoprotein; TSBP CTR9 SH2BP1, TSBP, p150, p150TSP CTR9 homolog, Paf1/RNA polymerase II complex component RNA polymerase-associated protein CTR9 homolog|Ctr9, Paf1/RNA polymerase II complex component, homolog|SH2 domain binding protein 1 (tetratricopeptide repeat containing)|TPR-containing, SH2-binding phosphoprotein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CTR9, check out the CTR9 Infographic

CTR9 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CTR9: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A05192-80ul

80 µl

$298
A05192-400ul

400 µl

$460

Free Secondary Antibody

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A05192
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$298.00

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