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Product Info Summary
| SKU: | A04760 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-Metalloreductase STEAP4 STEAP4 Antibody
View all STAMP2/STEAP4 Antibodies
SKU/Catalog Number
A04760
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Metalloreductase STEAP4 STEAP4 Antibody (Catalog # A04760). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
STEAP4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Metalloreductase STEAP4 STEAP4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04760)
Host
Rabbit
Contents
STEAP4 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
STEAP4 antibody was raised against a 14 amino acid synthetic peptide from near the center of human STEAP4. The immunogen is located within amino acids 210 - 260 of STEAP4.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least two isoforms are known to exist for this protein. This STEAP4 antibody does not cross-react with other STEAP proteins.
Reactive Species
A04760 is reactive to STEAP4 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
51981 MW
Background of STAMP2/STEAP4
The six-transmembrane epithelial antigen of prostate 4 (STEAP4) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP3), STEAP4 promotes both iron and copper reduction. STEAP4 is highly expressed in placenta, lung, heart and prostate tissues, and overexpressed in prostate cancer cells compared to normal prostate cells. Overexpression of STEAP4 in prostate cells significantly increases cell growth and colony formation, suggesting STEAP4 may have a role in cell proliferation and prostate cancer progression.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A04760 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
STEAP4 antibody can be used for detection of STEAP4 by Western blot at 0.5 - 1 μg/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of STEAP4 in rat liver tissue lysate with STEAP4 antibody at (A) 0.5 and (B) 1 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For STEAP4 (Source: Uniprot.org, NCBI)
Gene Name
STEAP4
Full Name
Metalloreductase STEAP4
Weight
51981 MW
Superfamily
STEAP family
Alternative Names
TIARP, STAMP2, TNFAIP9, Metalloreductase STEAP4, Six-transmembrane epithelial antigen of prostate 4 STEAP4 STAMP2, SchLAH, TIARP, TNFAIP9 STEAP4 metalloreductase metalloreductase STEAP4|STEAP family member 4|seven chromosome locus associated with HCC|six transmembrane prostate protein 2|six-transmembrane epithelial of prostate 4|sixTransMembrane protein of prostate 2|tumor necrosis factor, alpha-induced protein 9|tumor necrosis-alpha-induced adipose-related protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on STEAP4, check out the STEAP4 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for STEAP4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Metalloreductase STEAP4 STEAP4 Antibody (A04760)
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