Metalloreductase STEAP4 Antibodies

AND STEAP4 ELISA kits, Metalloreductase STEAP4 Proteins

Many biological assays use antibodies to detect Metalloreductase STEAP4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Metalloreductase STEAP4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Metalloreductase STEAP4 antibodies...

We validate the specificity of these antibodies to Metalloreductase STEAP4 by testing them on tissues known to express STEAP4 positively and negatively. Browse below to find the STEAP4 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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STEAP4 Infographic by Boster Bio

All STEAP4 Products

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Product

Figures

Specificity

Applications

Price

Anti-STEAP4/Stamp2 Antibody

1 Citations 6 Q&As

Human, Mouse, Rat

ELISA, IF, IHC-P, ICC

$335
Cat # A30510
100ul

Anti-Metalloreductase STEAP4 STEAP4 Antibody

Human, Mouse, Rat

ELISA, WB

$449
Cat # A04760
0.1 mg

Human STEAP4 Recombinant Protein

SDS-PAGE, Denatured

$250
Cat # PROTQ687X5
Starting from 20ug

STEAP4 (NM_024636) Human Over-expression Lysate

Human

$960
Cat # LS079689
100 µg

STEAP4 Overview

Facts about Metalloreductase STEAP4.

STEAP4 3D structure. Source: alphafold

Metalloreductase STEAP4 (STEAP4)

Metalloreductase that has the capacity to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+) (By similarity). Uses NADP(+) as acceptor (By similarity).

Plays a role in systemic metabolic homeostasis, including inflammatory and metabolic reactions (By similarity). Associated with obesity and insulin- resistance (PubMed:18430367, PubMed:18381574).

Gene Information

Human
Gene Name:	STEAP4
Uniprot:	Q687X5
Entrez:	79689

Family

Belongs to:

STEAP family

Alternative Names

EC 1.16.1; EC 1.16.1.-; FLJ23153; Six-transmembrane epithelial antigen of prostate 4; SixTransMembrane protein of prostate 2; STAMP2; STAMP2DKFZp666D049; STEAP family member 4; STEAP4; TIARP; TIARPsix transmembrane prostate protein 2; TNFAIP9; Tumor necrosis factor, alpha-induced protein 9metalloreductase STEAP4; tumor necrosis-alpha-induced adipose-related protein

Molecular Weight

Mass (kDA):
51.981 kDA

Genomic Context


Human

Location:	7q21.12
Sequence:	7; NC_000007.14 (88270892..88306894, complement)

Tissue Specificity

Ubiquitous. Highly expressed in adipose tissue. Expressed in placenta, lung, heart and prostate. Detected at lower levels in liver, skeletal muscle, pancreas, testis and small intestine. Highly expressed in joints of patients with rheumatoid arthritis and localized with CD68 cells, a marker for macrophages.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein.

Diseases

Obesity
Insulin Resistance
Insulin Sensitivity
Inflammation
Malignant Neoplasms
Metabolic Syndrome X
Neoplasms
Rheumatoid Arthritis
Diabetes Mellitus
Arthritis
Malignant Neoplasm Of Prostate
Hypertensive Disease

Prostatic Neoplasms
Dyslipidemias
Sarcoma
Ewings Sarcoma-primitive Neuroectodermal Tumor (pnet)
Acute Arthritis
Diabetes Mellitus, Non-insulin-dependent
Autoimmune Reaction

Pathways

Transport
Localization
Cell Proliferation
Cell Growth
Pathogenesis
Glucose Transport
Secretion
Adiponectin Secretion
Transmembrane Transport
Cell Migration
Demethylation

Macrophage Activation
Glucose Homeostasis
Rna Stabilization
Cell Cycle
Mrna Stabilization

PTMs

Phosphorylation

Demethylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/STEAP4

References

PMID: 15897894 by Korkmaz C.G., et al. Molecular cloning and characterization of STAMP2, an androgen- regulated six transmembrane protein that is overexpressed in prostate cancer.

PMID: 16227996 by Ohgami R.S., et al. Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells.

1 Publications of Boster Metalloreductase STEAP4 Antibodies & ELISA Kits

PubMed ID: 27808366, Expression and clinical significance of obesity-associated gene STEAP4 in obese ...

*More publications can be found for each product on its corresponding product page