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Product Info Summary
| SKU: | A05568-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Metalloreductase STEAP3 STEAP3 Antibody
View all STEAP3/TSAP6 Antibodies
SKU/Catalog Number
A05568-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Metalloreductase STEAP3 STEAP3 Antibody (Catalog # A05568-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
STEAP3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Metalloreductase STEAP3 STEAP3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05568-1)
Host
Rabbit
Contents
STEAP3 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
STEAP3 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human STEAP3. The immunogen is located within the first 50 amino acids of STEAP3.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
This STEAP3 antibody does not cross-react with other STEAP proteins.
Reactive Species
A05568-1 is reactive to STEAP3 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
54601 MW
Background of STEAP3/TSAP6
The six-transmembrane epithelial antigen of prostate 3 (STEAP3) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP4), STEAP3 promotes both iron and copper reduction. STEAP3 is highly expressed in hematopoietic tissues and colocalizes with the transferrin endosome. Overexpression of STEAP3 stimulates iron reduction; mice lacking STEAP3 are deficient in erythroid ferrireductase activity, suggesting that STEAP3 is an endosomal ferrireductase required for transferrin-dependent iron uptake in erythroid cells.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A05568-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
STEAP3 antibody can be used for detection of STEAP3 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of STEAP3 in HeLa cell lysate with STEAP3 antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of STEAP3 in mouse liver tissue with STEAP3 antibody at 2.5 μg/mL.
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Immunofluorescence of STEAP3 in Mouse Liver cells with STEAP3 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For STEAP3 (Source: Uniprot.org, NCBI)
Gene Name
STEAP3
Full Name
Metalloreductase STEAP3
Weight
54601 MW
Superfamily
STEAP family
Alternative Names
STMP3, TSAP6, AHMIO2, dudlin-2, Metalloreductase STEAP3, Dudulin-2, hTSAP6 STEAP3 AHMIO2, STMP3, TSAP6, dudlin-2, dudulin-2, pHyde STEAP3 metalloreductase metalloreductase STEAP3|STEAP family member 3, metalloreductase|six-transmembrane epithelial of prostate 3|tumor suppressor pHyde|tumor suppressor-activated pathway protein 6
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on STEAP3, check out the STEAP3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for STEAP3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Metalloreductase STEAP3 STEAP3 Antibody (A05568-1)
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